1st Edition

Nutraceuticals and Health Review of Human Evidence

Edited By Somdat Mahabir, Yashwant Pathak Copyright 2014
    396 Pages 17 B/W Illustrations
    by CRC Press

    396 Pages 17 B/W Illustrations
    by CRC Press

    Although health claims for nutraceuticals range from the fantastic to the sublime, most of these claims are based on cell culture studies and have not been validated in humans, making them inadequate for public health recommendations. Focusing on human population-based research (epidemiology studies), Nutraceuticals and Health: Review of Human Evidence explores the role of nutraceuticals in human health, disease prevention, health promotion, and as an adjunct to disease treatment.

    The editors and their team of recognized experts deliver a comprehensive scientific review of the latest research. The book opens with a general background of nutraceuticals and human health, then covers health and disease areas such as cancer, lipidermia and cardiovascular disease, metabolic syndrome with obesity, diabetes and hypertension, respiratory health, the gut microbiome, and cognitive decline. It then concludes by addressing the methodological issues that must be addressed in the conduct of epidemiological research on nutraceuticals in health and disease.

    Although nutraceuticals hold significant promise in alleviating the suffering from disease, for this potential to be fulfilled, much more research is needed to document safety and disease risks in humans. Addressing important knowledge gaps, the book includes cutting-edge summaries that highlight both the biological and epidemiological findings of relevant studies of nutraceuticals in health and disease. Taking an unusual, yet crucial epidemiological focus, it examines whether, and what kinds of, evidence exist to support a role for nutraceuticals in disease risk, prevention, and treatment.


    Background to Nutraceuticals and Human Health

    Dipanwita Dutta and Yashwant Pathak


    Clinical Trials of Dietary Supplements and Cancer

    Shanti D. Mahabir, Renjit Thomas, Somdat Mahabir

    Curcumin in Human Cancer Prevention and Treatment

    Adeeb Shezad and Young Sup Lee

    Cancer Prevention Potential of Diet and Dietary Supplements in Epigenome Modulation

    Zdenko Herceg

    Lipidemia and Cardiovascular Diseases

    Role of Dietary Supplements in LDL Cholesterol Lowering

    Prabhjot S. Nijjar

    Nutraceuticals and Atherosclerosis: Human trials

    Lina Badimon, Teresa Padro, Gemma Vilahur

    Nutraceuticals in Cardiovascular Disease: Mechanisms and Applications

    Srinivas M. Tipparaju, Jared Tur, Siva K. Panguluri

    Metabolic Syndrome: Obesity, Diabetes and Hypertension

    Potential of Nutraceuticals against Obesity Complications

    Kylie Conroy, Isobel Davidson and Mary Warnock

    The Role of Nutraceutical Supplements in the Prevention and Treatment of Hypertension

    Mark C. Houston

    Nutraceuticals in the Treatment of Metabolic Syndrome

    Francesco Visioli

    Medicinal Herbs and Dietary Supplements in Diabetes Management

    Poonam Tripathi and Awanish Kumar Pandey

    Respiratory Health

    Nutrients for Optimal Lung Function

    Susan Ettinger

    Gut Microbiome

    Nutraceutical-Gut Microbiome Interactions in Human Disease

    Mukesh Verma

    Metabolic and Potential Health Benefits of Nutraceuticals on Gut Micorbiome

    Malay K. Das and Yashwant Pathak

    Cognitive decline & Neurodegeneration

    Nutraceuticals in the Prevention of Cognitive Decline

    Zhenzhen Zhang and Joseph L Su

    Nutraceuticals in the Prevention or Treatment of Parkinson's Disease

    Elizabeth Mazzio, Fran Close, Karam Soliman

    Dietary Supplements and other Alternative Substances for the Treatment of Multiple Sclerosis

    Angela Senders, Rebecca Spain and Vijayshree Yadav

    Methodological Issues

    Methodological Issues Conducting Epidemiological Research on Nutraceuticals

    Somdat Mahabir


    Somdat Mahabir, Yashwant V. Pathak

    "… contributors review the latest research on nutraceuticals related to the prevention and treatment of cancer, cardiovascular disease, obesity, diabetes, hypertension, respiratory disease, cognitive disorders, Parkinson's disease, and multiple sclerosis. The book also considers the importance of nutraceuticals to the maintenance of the intestinal microbiome, and the methodological difficulties in conducting human research in this area. In the current relatively unregulated marketplace in the US, issues of safety and risk are at the forefront in the discussions. Recommended."
    —A. P. Boyar, CUNY Herbert H. Lehman College in CHOICE Magazine, June 2014