Nutrient-Gene Interactions in Health and Disease: 2nd Edition (Hardback) book cover

Nutrient-Gene Interactions in Health and Disease

2nd Edition

Edited by Naima Moustaid-Moussa, Carolyn D. Berdanier

CRC Press

496 pages | 100 B/W Illus.

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Hardback: 9780849322167
pub: 2001-05-30
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We have come to realize that optimal nutrient intake is determined by very specific genetic messages. This realization has led to an entirely new approach to understanding nutrition – the exploration of nutrient effects on gene expression.

Edited by leading experts in the field, Nutrient–Gene Interactions in Health and Disease provides an update of this important and rapidly growing field of research, presenting examples of both macronutrients and micronutrients as they affect gene expression. It addresses lipogenesis, fatty acid oxidation, fatty acid desaturation, and glucose transporters. It also discusses genes that associate with obesity or cancer, genes that are affected by vitamins A and D, and several other topics.

Genetic regulation of nutritional response is at the heart of our understanding of nutrition science. Nutrient–Gene Interactions in Health and Disease presents the latest information about how specific processes in intermediary metabolism are genetically regulated, giving you a new understanding of such diseases as obesity, diabetes, alcoholism, anemia, and other diseases with both a nutrient and a genetic component.


“…a good resource for researchers in the area of biochemistry, nutritional sciences, cell biology, genetics and physiology, especially those interested in lipid metabolism.”

— Journal of Nutrition Education and Behavior

Table of Contents

Dietary and Hormonal Regulation of the Mammalian Fatty Acid Synthase Gene, Kristin Morris, Yanxin Wang, Suyeon Kim, and Naima Moustaïd-Moussa

Nutrition and Adipocyte Gene Expression, Ron F. Morrison and Stephen R. Farmer

Regulation of the Stearoyl-CoA Desaturase Genes by Dietary Fat: Role of Polyunsaturated Fatty Acids, James M. Ntambi and Young-Cheul Kim

Fatty Acids, White Adipose Tissue Development and Adipocyte Differentiation, Gérard Ailhaud

Acyl-CoA Synthetase 1: Regulation and Role in Metabolism, Pamela J. Smith

Nutritional Regulation of Fatty Acid Transport Protein Expression, Judith Storch and Fiona M. Herr

Alcohol and Gene Expression in the Central Nervous System, Matthew T. Reilly, Christoph Fehr, and Kari J. Buck

Nutrient Control of Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes, Joseph P. Hwang, Greg Marshall, Daniel Fallon, and Susan C. Frost

Prohormone Processing and Disorders of Energy Homeostasis, Jung Han Kim and Jürgen K. Naggert

The Agouti Gene in Obesity: Central and Peripheral Mechanisms, and Therapeutic Implications, Michael B. Zemel, Ph.D., Bingzhong Xue, B. Med, and Hang Shi, B. Med

Dietary Fats and APC-Driven Intestinal Tumorigenesis, Jay Whelan and Michael F. McEntee

Body Weight Regulation, Uncoupling Proteins, and Energy Metabolism, Sheila Collins, Wenhong Cao, Tonya M. Dixon, Kiefer W. Daniel, Hiroki Onuma, and Alexander V. Medvedev

Vitamin A and Gene Expression, Peter McCaffery, Fausto Andreola, Valeria Giandomenico, and Luigi M. De Luca

Vitamin A and Mitochondrial Gene Expression, Helen B. Everts and Carolyn D. Berdanier

Vitamin D and Gene Expression, Anthony W. Norman and Elaine D. Collins

Vitamin E and Gene Expression, Simin Nikbin Meydani, Kate J. Claycombe, and Catarina Sacristán

Differential Regulation and Function of Glutathione Peroxidases and other Selenoproteins, Xin Gen Lei

Ferritin: A Novel Human Ferritin Heavy-Chain MRNA is Predominantly Expressed in the Adult Brain, Madhu S. Dhar

About the Series

Modern Nutrition

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biochemistry
MEDICAL / Nutrition