1st Edition

Orthopaedics
Principles of Basic and Clinical Science



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ISBN 9780849392375
Published June 24, 1999 by CRC Press
312 Pages

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Book Description

In Orthopaedics: Principles of Basic and Clinical Science, experts in the field summarize the latest findings to allow professionals to keep abreast of this complex area and to apply the information in their practice. You'll find the latest research developments in:
*The biology of bone, its structure, function, and development
*The metabolism of calcium and phosphorus
*Systemic and local regulators of mineral and bone metabolism, including the growing field of cytokines

Plus the newest information on clinical topics including:
*Biomechanics
*Infection
*Tumors
*Fractures and fracture healing
*The biology of prostheses

Table of Contents

Bone as Tissue
Structure and Function of Bone Tissue-Webster S. S. Jee, Ph.D.
Morphology: Macroscopic and Microscopic Structures
Skeletal Development
Development of a Typical Long Bone
Skeletal Mass and Its Change
Structure and Function of Connective Tissue-Joel Rosenbloom, M.D., Ph.D.
The Collagens
The Elastic Fiber
Other Matrix Proteins
Proteoglycans
Biology of Osteoclasts and Osteoblasts-Edward J. Puzas, Ph.D.
Osteoclast
Bone Resorption
Osteoblast
Bone Formation
Skeletal Remodeling
Heritable Diseases of Bone and Connective Tissue-Deborah Redford-Badwal, D.D.S., Ph.D. and David W. Rowe, M.D.
Organization of the Extracellular Matrix
Biosyntheses of Type I Collagen
Concepts Important to Understanding the Mutations That Result in Heritable Connective Tissue Disorders
Connective Tissue Diseases
Osteoporosis-Felix Bronner, Ph.D.
Calcium in Bone
The Effect of Aging on the Skeleton
Gonadal Hormones as Major Regulators of Bone Cell Function
Cellular Effects of Gonadal Hormones
Therapy Considerations
Mineral Metabolism of Bone
Calcium Metabolism and Homeostasis-Felix Bronner, Ph.D.
Calcium in Food and Diet
Calcium Absorption
Calcium in Blood
Calcium in Bone
Calcium Excretion
Calcium Requirement
Metabolism of Phosphate and Metals-Felix Bronner, Ph.D.
Phosphate Metabolism
Metals in Bone
The Calcitropic Hormones: Parathyroid Hormone, Calcitonin, Vitamin D-Felix Bronner, Ph.D.
Parathyroid Hormone
Parathyroid Hormone Related Peptides
Calcitonin
Vitamin D
Systemic and Local Modifiers of Bone Metabolism Other Than the Calcitropic Hormones-Felix Bronner, Ph.D.
Gonadal Sateroids
Coricosteroids
Thyroid Hormones
Growth Hormone and Somatomedins
(Insulin Growth Factors)
Insulin and Glucagon
Prostaglandins and Cytokines
Metabolic Disease-Michael Kleerekoper, M.D.
Osteoporosis
Primary Hyperparathyroidism
Hyperparathyroidism Secondary to Renal Failure (Renal Osteodystrophy)
Paget's Disease of Bone
Osteomalacia
Clinical Topics
The Normal and Diseased Joint-Wilmer L. Sibbitt, Jr., M.D.
The Normal Joint
The Diseased Joint
Noninflammatory Disease of Joints
Neuromuscular Function and the Skeleton-George E. Omer, Jr., M.D.
Normal Peripheral Nerve and Skeletal Muscle Function
The Injured Nerve and Denervated Skeletal Muscle
Peripheral Nerve Repair
Nerve Regeneration after Repair
Biomedical Principles Applied to Skeletal Function-Thomas A. DeCoster, M.D. and Brian Robinson, M.D.
Principles and Definitions of Mechanics
Biomechanisms of Musculoskeletal Tissue
Skeletal Fixation
Healing of Bone and Connective Tissues-Andrew E. Caputo, M.D.
Healing
Ligament
Tendon
Bone Healing
Bone Tumors and Tumor-Like Lesions-Richard V. Worrell, M.D.
Classification
Staging
Diagnostic Studies
Treatment Options
Representative Case Studies
Infectious Diseases of Bone-Richard V. Worrell, M. D.
Pyogenic Osteomyelitis
Diagnostic Findings in Pyogenic Osteomyelitis
Treatment Strategies in Pyogenic Osteomyelitis
Nonpyogenic Osteomyelitis
The Foot-Richard A. Miller, M.D. and David M. Bloom, M.D.
Anatomy and Biomechanics
Radiography
Traumatic Disorders of the Foot
Infectious Disorders of the Foot
Arthritic Conditions of the Foot
Common Foot Pathologies
The Hand-Charles Prybil, M.D. and Moneb Moneim, M.D.
Anatomy of Hand and Wrist
Amputations, Arthrodesis and Arthroplasty
Management Principles for Fractures, Dislocations, Infections and Tendon Injury
Prosthetic Implants and Total Joint Arthroplasty-Richard V. Worrell, M.D.
Hip Arthroplasty
Knee Arthroplasty

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