Orthopaedics: Principles of Basic and Clinical Science, 1st Edition (Hardback) book cover


Principles of Basic and Clinical Science, 1st Edition

Edited by Felix Bronner, Richard V. Worrell

CRC Press

312 pages

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Hardback: 9780849392375
pub: 1999-06-24
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In Orthopaedics: Principles of Basic and Clinical Science, experts in the field summarize the latest findings to allow professionals to keep abreast of this complex area and to apply the information in their practice. You'll find the latest research developments in:

*The biology of bone, its structure, function, and development

*The metabolism of calcium and phosphorus

*Systemic and local regulators of mineral and bone metabolism, including the growing field of cytokines

Plus the newest information on clinical topics including:




*Fractures and fracture healing

*The biology of prostheses

Table of Contents

Bone as Tissue

Structure and Function of Bone Tissue-Webster S. S. Jee, Ph.D.

Morphology: Macroscopic and Microscopic Structures

Skeletal Development

Development of a Typical Long Bone

Skeletal Mass and Its Change

Structure and Function of Connective Tissue-Joel Rosenbloom, M.D., Ph.D.

The Collagens

The Elastic Fiber

Other Matrix Proteins


Biology of Osteoclasts and Osteoblasts-Edward J. Puzas, Ph.D.


Bone Resorption


Bone Formation

Skeletal Remodeling

Heritable Diseases of Bone and Connective Tissue-Deborah Redford-Badwal, D.D.S., Ph.D. and David W. Rowe, M.D.

Organization of the Extracellular Matrix

Biosyntheses of Type I Collagen

Concepts Important to Understanding the Mutations That Result in Heritable Connective Tissue Disorders

Connective Tissue Diseases

Osteoporosis-Felix Bronner, Ph.D.

Calcium in Bone

The Effect of Aging on the Skeleton

Gonadal Hormones as Major Regulators of Bone Cell Function

Cellular Effects of Gonadal Hormones

Therapy Considerations

Mineral Metabolism of Bone

Calcium Metabolism and Homeostasis-Felix Bronner, Ph.D.

Calcium in Food and Diet

Calcium Absorption

Calcium in Blood

Calcium in Bone

Calcium Excretion

Calcium Requirement

Metabolism of Phosphate and Metals-Felix Bronner, Ph.D.

Phosphate Metabolism

Metals in Bone

The Calcitropic Hormones: Parathyroid Hormone, Calcitonin, Vitamin D-Felix Bronner, Ph.D.

Parathyroid Hormone

Parathyroid Hormone Related Peptides


Vitamin D

Systemic and Local Modifiers of Bone Metabolism Other Than the Calcitropic Hormones-Felix Bronner, Ph.D.

Gonadal Sateroids


Thyroid Hormones

Growth Hormone and Somatomedins

(Insulin Growth Factors)

Insulin and Glucagon

Prostaglandins and Cytokines

Metabolic Disease-Michael Kleerekoper, M.D.


Primary Hyperparathyroidism

Hyperparathyroidism Secondary to Renal Failure (Renal Osteodystrophy)

Paget's Disease of Bone


Clinical Topics

The Normal and Diseased Joint-Wilmer L. Sibbitt, Jr., M.D.

The Normal Joint

The Diseased Joint

Noninflammatory Disease of Joints

Neuromuscular Function and the Skeleton-George E. Omer, Jr., M.D.

Normal Peripheral Nerve and Skeletal Muscle Function

The Injured Nerve and Denervated Skeletal Muscle

Peripheral Nerve Repair

Nerve Regeneration after Repair

Biomedical Principles Applied to Skeletal Function-Thomas A. DeCoster, M.D. and Brian Robinson, M.D.

Principles and Definitions of Mechanics

Biomechanisms of Musculoskeletal Tissue

Skeletal Fixation

Healing of Bone and Connective Tissues-Andrew E. Caputo, M.D.




Bone Healing

Bone Tumors and Tumor-Like Lesions-Richard V. Worrell, M.D.



Diagnostic Studies

Treatment Options

Representative Case Studies

Infectious Diseases of Bone-Richard V. Worrell, M. D.

Pyogenic Osteomyelitis

Diagnostic Findings in Pyogenic Osteomyelitis

Treatment Strategies in Pyogenic Osteomyelitis

Nonpyogenic Osteomyelitis

The Foot-Richard A. Miller, M.D. and David M. Bloom, M.D.

Anatomy and Biomechanics


Traumatic Disorders of the Foot

Infectious Disorders of the Foot

Arthritic Conditions of the Foot

Common Foot Pathologies

The Hand-Charles Prybil, M.D. and Moneb Moneim, M.D.

Anatomy of Hand and Wrist

Amputations, Arthrodesis and Arthroplasty

Management Principles for Fractures, Dislocations, Infections and Tendon Injury

Prosthetic Implants and Total Joint Arthroplasty-Richard V. Worrell, M.D.

Hip Arthroplasty

Knee Arthroplasty

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Anatomy
MEDICAL / Surgery / General