Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome: 1st Edition (e-Book) book cover

Oxidative Stress and Inflammatory Mechanisms in Obesity, Diabetes, and the Metabolic Syndrome

1st Edition

Edited by Helmut Sies

CRC Press

344 pages

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Description

Characterized by obesity, insulin resistance, dyslipidemia, and hypertension, metabolic syndrome is associated with the risks of type 2 diabetes mellitus and cardiovascular disease. Obesity, which increases the incidence of atherosclerotic cardiovascular disease and subsequently leads to increased stress and inflammation, appears to play a central

Table of Contents

The Metabolic Syndrome Defined. The Metabolic Syndrome: The Question of Balance between the Pro-Inflammatory Effect of Macronutrients and the Anti-Inflammatory Effect of Insulin. The Role of Oxidative Stress in Diseases Associated with Overweight and Obesity. Metabolic Syndrome Due to Early Life Nutritional Modifications. Oxidative Stress and Antioxidants in Perinatal Period. Maternal Obesity, Glucose Intolerance, and Inflammation in Pregnancy. Obesity, Nutrigenomics, Metabolic Syndrome, and Type 2 Diabetes. Post-Prandial Endothelial Dysfunction, Oxidative Stress, and Inflammation in Type 2 Diabetes. Obesity and Inflammation: Implications for Atherosclerosis. Oligomeric Composition of Adiponectin and Obesity. Insulin-Stimulated Reactive Oxygen Species and Insulin Signal Transduction. Intracellular Signaling Pathways and Perixosome Proliferator-Activated Receptors in Vascular Health in Hypertension and in Diabetes. Role of Uncoupling Protein 2 in Pancreatic Cell Function: Secretion and Survival. Nutritional Modulation of Inflammation in Metabolic Syndrome. Dietary Fatty Acids and Metabolic Syndrome. Lipid-Induced Death of Macrophages: Implication for Destabilization of Atherosclerotic Plaques. a-Lipoic Acid Prevents Diabetes Mellitus and Endothelial Dysfunction in Diabetes-Prone Obese Rats. Lipoic Acid Blocks Obesity through Reduced Food Intake, Enhanced Energy Expenditure, and Inhibited Adipocyte Differentiation. Effects of Conjugated Linoleic Acid and Lipoic Acid on Insulin Action in Insulin-Resistant Obese Zucker Rats. Trivalent Chromium Supplementation Inhibits Oxidative Stress, Protein Glycosylation, and Vascular Inflammation in High Glucose-Exposed Human Erythrocytes and Monocytes. Index.

Subject Categories

BISAC Subject Codes/Headings:
MED027000
MEDICAL / Endocrinology & Metabolism
MED060000
MEDICAL / Nutrition
SCI017000
SCIENCE / Life Sciences / Cytology
TEC012000
TECHNOLOGY & ENGINEERING / Food Science