2nd Edition
Particle-Lung Interactions
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.
Structure and Function of the Lung
Functional Aspects of Lung Structure as Related to Interaction with Particles, Christian M€uhlfeld and Matthias Ochs
Particle Characteristics
Ambient Tropospheric Particles, Paul A. Solomon and Daniel L. Costa
Manufactured Nanoparticles, Robert N. Grass, Ludwig K. Limbach, and Wendelin J. Stark
Particulate Carriers for Pulmonary Drug Delivery, Stephanie Hein, Andreas Henning, Michael Bur, Marc Schneider, and Claus-Michael Lehr
Inhalation of Particles
Deposition, Retention and Clearance, and Translocation of Inhaled Fine and Nano-Sized Particles
in the Respiratory Tract, Winfried M€oller, Wolfgang G. Kreyling, Otmar Schmid, Manuela Semmler-Behnke, and Holger Schulz
Health Effects of Particle Inhalation
The Epidemiology of Particle Health Effects, Joel Schwartz
Cardiovascular Consequences of Particles, Mark W. Frampton, Mark J. Utell, and Jonathan M. Samet
Autonomic Mediation of the Cardiac Responses to Particle Exposure, Beatriz Gonzalez-Flecha
Effects of Airborne Particles on Respiratory Viral Infection, Ilona Jaspers and Katherine Horvath
Airborne Particles and Structural Remodeling of the Lungs, Amy K. Madl, Christopher Carosino, and Kent E. Pinkerton
Cellular and Molecular Mechanisms of Particle Health Effects
Effect of Particles on Mucus and Mucociliary Clearance, Malcolm King
The Role of Surfactant in Particle Exposure, Francis H. Y. Green, Samuel Sch€urch, Matthias Amrein, Peter J. Gerber, and Zoya Leonenko
Nanoparticle–Cell Membrane Interactions, Barbara Rothen-Rutishauser, Fabian Blank, Christian M€uhlfeld, and Peter Gehr
Mechanisms and Processes Underlying Toxicological Responses to Particles, Vicki Stone and Ken Donaldson
Aeroallergen-Lung Interactions, Carsten Schleh and Jens M. Hohlfeld
Dose-Response Relationships, Tobias Stoeger and Otmar Schmid
Index
Biography
Peter Gehr, University of Berne, Switzerland. Christian Mühlfeld, University of Giessen, Germany. Barbara Rothen-Rutishauser, University of Berne, Switzerland. Fabian Blank University of Berne, Switzerland.
