This book is the definitive work on the theory and practice of pharmaceutical tablet and pellet coating. It describes both the practical and theoretical aspects of tablet coating, including the equipment and methods used in laboratory development, scale-up and production systems, More…as well as automation and validation. This book also discusses the problems of conforming to world-wide regulations, and the hazards of environmental pollution.
1. Introduction and overview of pharmaceutical coating 2. Film-coating materials and their properties 3. Sugar coating 4. Solution properties and atomization in film coating 5. Surface effects in film coating 6. The development of film-coating processes 7. The coating process 8. Coating pans and coating columns 9. Environmental considerations: Treatment of exhaust gases from film-coating processes 10. Automation of coating processes 11. Validation of tablet coating processes 12. Mechanical properties of film coats 13. Film coat quality 14. Modified release coatings 15. Some common practical questions and suggested answers 16. Bibliography