Pharmaceutical Powder ComPattion Technology: 1st Edition (Hardback) book cover

Pharmaceutical Powder ComPattion Technology

1st Edition

Edited by Goran Alderborn, Christer Nystrom

CRC Press

634 pages

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Description

This unique reference examines the modern pharmaceutical compacting techniques used to form tablets out of powders-describing the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.

Table of Contents

Interparticulate Bonding Characteristics of Pharmaceutical Compacts

Interparticulate Attraction Mechanisms, Claus Führer

The Importance of Intermolecular Bonding Forces and the Concept of Bonding Surface Area, Christer Nyström and Per-Gunnar Karehill

Characterization of the Compression Process

Porosity-Pressure Functions, Petteri Paronen and Jukka Ilkka

Force-Displacement and Network Measurements, Gert Ragnarsson

Viscoelastic Models, Fritz Müller

Application of Percolation Theory and Fractal Geometry to Tablet Compaction, Hans Leuenberger, Ruth Leu, and Jean-Daniel Bonny

Characterization of Compact Properties

Mechanical Strength, Peter N. Davies and J. Michael Newton

Tablet Surface Area, N. Anthony Armstrong

Rationale for and the Measurement of Tableting Indices, Everett N. Hiestand

Material Properties of Importance for Powder Volume Reduction and Compact Strength

Particle Dimensions, Göran Alderborn

Mechanical Properties, Ray C. Rowe and Ron J. Roberts

Granule Properties, Göran Alderborn and Martin Wikberg

Modeling the Compression Behavior of Particle Assemblies from the Mechanical Properties of Individual Particles, Wendy C. Duncan-Hewitt

Compaction Properties of Excipients and Powder Mixtures

Materials for Direct Compaction, Gerald K. Bolhuis and Zak T. Chowhan

Compaction Properties of Binary Mixtures, John T. Fell

Lubricant Sensitivity, Gerad K. Bolhuis and Arne W. Hölzer

The Development and Optimization of Tablet Formulations Using Mathematical Methods, Fridrun Podczeck

About the Editors

Göran Alderborn, Christer Nyström

Subject Categories

BISAC Subject Codes/Headings:
MED071000
MEDICAL / Pharmacology
SCI013000
SCIENCE / Chemistry / General