Physics of Thermal Therapy: Fundamentals and Clinical Applications, 1st Edition (Hardback) book cover

Physics of Thermal Therapy

Fundamentals and Clinical Applications, 1st Edition

Edited by Eduardo Moros

CRC Press

380 pages | 15 Color Illus. | 281 B/W Illus.

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Hardback: 9781439848906
pub: 2012-12-05
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The field of thermal therapy has been growing tenaciously in the last few decades. The application of heat to living tissues, from mild hyperthermia to high-temperature thermal ablation, has produced a host of well-documented genetic, cellular, and physiological responses that are being researched intensely for medical applications, particularly for treatment of solid cancerous tumors using image guidance. The controlled application of thermal energy to living tissues has proven a great challenge, requiring expertise from multiple disciplines, thereby leading to the development of many sophisticated pre-clinical and clinical devices and treatment techniques. Physics of Thermal Therapy: Fundamentals and Clinical Applications captures the breadth and depth of this highly multidisciplinary field.

Focusing on applications in cancer treatment, this book covers basic principles, practical aspects, and clinical applications of thermal therapy. An overview of the fundamentals shows how use of controlled heat in medicine and biology involves electromagnetics, acoustics, thermodynamics, heat transfer, and imaging sciences. The book discusses challenges in the use of thermal energy on living tissues and explores the genetic, cellular, and physiological responses that can be employed in the fight against cancer from the physics and engineering perspectives. It also highlights recent advances, including the treatment of solid tumors using image-guided thermal therapy, microbubbles, nanoparticles, and other cutting-edge techniques.


"This long overdue volume offers a richly enhanced update on these classic texts, and adds numerous chapters on new areas of research and clinical activity. It is a well-rounded, balanced presentation of the current status of the field of thermal medicine, and is packed with useful new material."

Medical Physics, June 2013

Table of Contents

Foundations of Thermal Therapy Physics

Fundamentals of Bioheat Transfer

Kenneth R. Diller

Thermal Dose Models: Irreversible Alterations in Tissues

John A. Pearce

Practical Clinical Thermometry

R. Jason Stafford and Brian A. Taylor

Physics of Electromagnetic Energy Sources

Jeffrey W. Hand

The Physics of Ultrasound Energy Sources

V. Bull and Gail R. ter Haar

Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy: Ultrasound

Robert J. McGough

Numerical Modeling for Simulation and Treatment Planning of Thermal Therapy

Esra Neufeld, Maarten Paulides, Gerard van Rhoon, and Niels Kuster

Clinical Thermal Therapy Systems

External Electromagnetic Methods and Devices

Gerard C. van Rhoon

Interstitial Electromagnetic Devices for Thermal Ablation

Dieter Haemmerich and Chris Brace

Clinical External Ultrasonic Treatment Devices

Lili Chen, Faqi Li, Feng Wu, and Eduardo G. Moros

Endocavity and Catheter-Based Ultrasound Devices

Chris J. Diederich

Physical Aspects of Emerging Technology for Thermal Therapy

Evolving Tools for Navigated Image-Guided Thermal Cancer Therapy

Kevin Cleary, Emmanuel Wilson, and Filip Banovac

Temperature Imaging Using Ultrasound

R. Martin Arthur

Focused Ultrasound Applications for Brain Cancer

Meaghan A. O’Reilly and Kullervo Hynynen

Extracorporeal Ultrasound-Guided High-Intensity Focused Ultrasound Ablation for Cancer Patients

Feng Wu

Using Hyperthermia to Augment Drug Delivery

Mark W. Dewhirst

Magnetic Nanoparticles for Cancer Therapy

Michael L. Etheridge, John C. Bischof, and Andreas Jordan

Application of Gold Nanoparticles in Laser Thermal Therapy

Zhenpeng Qin and John C. Bischof

Thermochemical Ablation

Erik N. K. Cressman

About the Series

Imaging in Medical Diagnosis and Therapy

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
MEDICAL / Oncology
SCIENCE / Physics