Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individu
Part I General Perspectives. Old Age as a Stage of Life: Common Terms Related to Aging and Methods Used to Study Aging. Human Longevity in Historical Perspective. Comparative Aging, Geriatric Functional Assessment, Aging, and Disease. Cellular Senescence, Cell Death, and Transgenic Mouse Models of Aging. Theories of Life Span and Aging Part II Systemic and Organismic Aging.. The Nervous System: Structural, Biochemical, Metabolic, and Circulatory Changes. The Nervous System: Functional Changes with Aging. Sensory Systems: Normal Aging, Disorders, and Treatments of Vision and Hearing in Humans. The Adrenals and Pituitary, Stress, Adaptation, and Longevity. Female Reproductive Aging and Menopause. The Ensemble Male Hypothalamo-Pituitary-Gonadal Axis. The Thyroid, Parathyroid, and Pineal Glands. The Endocrine Pancreas, Obesity, and Diffuse Endocrine and Chemical Mediators. The Immune System. Cardiovascular Alterations with Aging: Atherosclerosis and Coronary Heart Disease. Lipids, Lipoproteins, and Atherosclerosis., The Pulmonary Respiratory System: Hematopoiesis and Erythrocytes, The Kidney, the Lower Urinary Tract, Body Fluids, and the Prostate. The Gastrointestinal Tract and the Liver. The Skeleton, Joints, and Skeletal and Cardiac Muscles. The Skin. Part III Prevention and Rehabilitation. Pharmacology and Drug Management in the Elderly. Healthful Aging: Nutrition and Experimental Strategies in Dietary Restriction. Benefits of Physical Exercise. Regenerative Perspectives and Assistive Technologies.