Pioneering Stem Cell/Gene Therapy Trials: 1st Edition (Hardback) book cover

Pioneering Stem Cell/Gene Therapy Trials

1st Edition

By Roger Bertolotti

CRC Press

330 pages

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Hardback: 9789067643948
pub: 2003-10-15
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Description

The first unequivocal success for Gene Therapy was reported in April 2000 for X-SCID patients. Pioneering stem cell/gene therapy clinical trials are the focus of this book. Therapy successes such as the X-SCID trial and improved ADA-SCID ones are presented together with pioneering angio/vasculogenic clinical trials mediated either by transient gene therapy or emerging autologous stem cell transplantation. Highlights also include 1) promises of the breakthrough combination of stem cell- and transient gene-therapy, 2) gene therapy trials for neurodegenerative disease on non-human primates where long-term gene therapy might involve brain stem cells, and 3) the first clinical trial with non-invasive monitoring of therapeutic gene expression as a prospective conclusion. This volume will be of value and interest to researchers in this exciting field.

Subject Categories

BISAC Subject Codes/Headings:
SCI029000
SCIENCE / Life Sciences / Genetics & Genomics