Plants that Fight Cancer: 1st Edition (Hardback) book cover

Plants that Fight Cancer

1st Edition

Edited by Spiridon E. Kintzios, Maria G. Barberaki

CRC Press

312 pages | 123 B/W Illus.

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Hardback: 9780415298537
pub: 2004-01-15
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Description

An increasing amount of cancer research is being directed towards the investigation of plant-derived anticancer compounds, many of which have been used in traditional herbal treatments for centuries. Plants that Fight Cancer is an up-to-date, extensive review of plant genera and species with documented anti-tumor and anti-leukaemic properties. Following an overview of the disease and the diverse methods of therapy and clinical testing, the book provides a detailed examination of the plants whose compounds are currently used in conventional cancer treatment, the species which show the greatest potential as future candidates, and other species with established anticancer properties. The third section explores each of more than 150 terrestrial plant genera and species, with a review of their traditional uses, mythology, botany, active ingredients, and product applications, along with photographs and illustrations and an analysis of expected results and risks. The text closes with a discussion of algal extracts and isolated metabolites with anticancer activity, a summary of published research for each species, and chemical structures of the most important compounds.

Table of Contents

PART I: WHAT DO WE KNOW ABOUT CANCER AND ITS THERAPY?

Incidence and Causes

Classification of Cancer Types

Therapy

Conventional Cancer Treatments

Advanced Cancer Treatments

Other Advanced Therapies

Alternative Cancer Treatments

From Source to Patient: Testing the Efficiency of a Candidate Anticancer Drug

Preclinical Tests

Phases of Clinical Trials

Clinical Trial Protocols

PART II: PLANTS AND CANCER

Brief Overview of the General Organization of the Plant Cell

The Chemical Constituents of the Plant Cell

Primary Metabolites

Secondary Metabolites

Why Do Plant Compounds Have an Anticancer Activity?

Chemical Groups of Natural Products with Anticancer Properties

Alkaloids

Polysaccharides

Glycosides

Lipids (Saponifiable)

Flavonoids

Proteins

Annonaceous Acetogenins

Terpenoids

Nucleic Acids

Lignans

Phenols and Derivatives

Aldehydes

Unsaponifiable Lipids

Unidentified Compounds

Biotechnology and the Supply Issue

PART III: TERRESTRIAL PLANT SPECIES WITH ANTICANCER ACTIVITY: A PRESENTATION

Introduction: General Botanical Issues

Species-specific Information

The Guardian Angels: Plant Species Used in Contemporary Clinical Cancer Treatment

Promising Candidates for the Future: Plant Species with a Laboratory-Proven Potential

The Fable: Where Tradition Fails to Meet Reality

Other Species with Documented Anticancer Activities

PART IV: CYTOTOXIC METABOLITES FROM MARINE ALGAE

Introduction

Cytotoxic Metabolites from Chlorophyta

Cytotoxic Metabolites from Rhodophyta

Cytotoxic Metabolites from Phaeophyta

Cytotoxic Metabolites from Microalgae

Conclusions

References

APPENDIX: CHEMICAL STRUCTURES OF SELECTED COMPOUNDS

References

Chemical Index

Species Index

Subject Categories

BISAC Subject Codes/Headings:
HEA011000
HEALTH & FITNESS / Herbal Medications
SCI011000
SCIENCE / Life Sciences / Botany
SCI013000
SCIENCE / Chemistry / General