Polymeric Biomaterials: Structure and Function, Volume 1, 1st Edition (Hardback) book cover

Polymeric Biomaterials

Structure and Function, Volume 1, 1st Edition

Edited by Severian Dumitriu, Valentin Popa

CRC Press

920 pages | 404 B/W Illus.

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Biomaterials have had a major impact on the practice of contemporary medicine and patient care. Growing into a major interdisciplinary effort involving chemists, biologists, engineers, and physicians, biomaterials development has enabled the creation of high-quality devices, implants, and drug carriers with greater biocompatibility and biofunctionality. The fast-paced research and increasing interest in finding new and improved biocompatible or biodegradable polymers has provided a wealth of new information, transforming this edition of Polymeric Biomaterialsinto a two-volume set.

This volume, Polymeric Biomaterials: Structure and Function, contains 25 authoritative chapters written by experts from around the world. Contributors cover the following topics:

  • The structure and properties of synthetic polymers including polyesters, polyphosphazenes, and elastomers
  • The structure and properties of natural polymers such as mucoadhesives, chitin, lignin, and carbohydrate derivatives
  • Blends and composites—for example, metal–polymer composites and biodegradable polymeric/ceramic composites
  • Bioresorbable hybrid membranes, drug delivery systems, cell bioassay systems, electrospinning for regenerative medicine, and more

Completely revised and expanded, this state-of-the-art reference presents recent developments in polymeric biomaterials: from their chemical, physical, and structural properties to polymer synthesis and processing techniques and current applications in the medical and pharmaceutical fields.


"This book is a valuable source of data on the complex subject of polymeric biomaterials, written by world-renowned scientists with major contributions in this field and reflects the current state of knowledge of nearly the entire spectrum of polymeric biomaterials.

—Diana Ciolacu, Cellulose Chem. Technol., 47(5-6), 487-494 (2013)

Table of Contents

Synthesis and Fabrication of Polyesters as Biomaterials

Philippe Lecomte and Christine Jérôme

Hydrogels Formed by Cross-Linked Poly(Vinyl Alcohol)

Gaio Paradossi

Development and Evaluation of Poly(Vinyl Alcohol) Hydrogels as a Component of Hybrid Artificial Tissues for Orthopedics Surgery Application

Masanori Kobayashi

Polyphosphazenes as Biomaterials

Meng Deng, Cato T. Laurencin, Harry R. Allcock, and Sangamesh G. Kumbar

Biodegradable Polymers as Drug Carrier Systems

Abraham J. Domb and Wahid Khan

Bioresorbable Hybrid Membranes for Bone Regeneration

Akiko Obata and Toshihiro Kasuga

Mucoadhesive Polymers: Basics, Strategies, and Future Trends

Andreas Bernkop-Schnürch

Biodegradable Polymeric/Ceramic Composite Scaffolds to Regenerate Bone Tissue

Catherine Gkioni, Sander Leeuwenburgh, and John Jansen

Amphiphilic Systems as Biomaterials Based on Chitin, Chitosan, and Their Derivatives

Jacques Desbrieres

Biomaterials of Natural Origin in Regenerative Medicine

Vijay Kumar Nandagiri, Valeria Chiono, Piergiorgio Gentile, Franco Maria Montevecchi, and Gianluca Ciardelli

Natural Polymers as Components of Blends for Biomedical Applications

Alina Sionkowska

Metal–Polymer Composite Biomaterials

Takao Hanawa

Evolution of Current and Future Concepts of Biocompatibility Testing

Menno L.W. Knetsch

Biocompatibility of Elastomers

Dominique Chauvel-Lebret, Pascal Auroy, and Martine Bonnaure-Mallet

Preparation and Applications of Modulated Surface Energy Biomaterials

Blanca Vázquez, Luis M. Rodríguez-Lorenzo, Gema Rodríguez-Crespo, Juan Parra, Mar Fernández, and Julio San Román

Electrospinning for Regenerative Medicine

Toby D. Brown, Cedryck Vaquette, Dietmar W. Hutmacher, and Paul D. Dalton

Polymeric Nanoparticles for Targeted Delivery of Bioactive Agents and Drugs

Cesare Errico, Alberto Dessy, Anna Maria Piras, and Federica Chiellini

Polymeric Materials Obtained through Biocatalysis

Florin Dan Irimie, Csaba Paizs, and Monica Ioana Tosa

Polymer-Based Colloidal Aggregates as a New Class of Drug Delivery Systems

Cesare Cametti

Photoresponsive Polymers for Control of Cell Bioassay Systems

Kimio Sumaru, Shinji Sugiura, Toshiyuki Takagi, and Toshiyuki Kanamori

Lignin in Biological Systems

Valentin I. Popa

Carbohydrate-Derived Self-Crosslinkable In Situ Gelable Hydrogels for Modulation of Wound Healing

Lihui Weng, Christine Falabella, and Weiliam Chen

Dental and Maxillofacial Surgery Applications of Polymers

E.C. Combe

Biomaterials as Platforms for Topical Administration of Therapeutic Agents in Cutaneous Wound Healing

Rhiannon Braund and Natalie J. Medlicott

Polymers for Artificial Joints

Masayuki Kyomoto, Toru Moro, and Kazuhiko Ishihara

About the Editors

Severian Dumitriu (deceased) was a research professor in the Department of Chemical Engineering at the University of Sherbrooke, Quebec, Canada. He edited several books, including Polymeric Biomaterials, Second Edition, Polysaccharides in Medicinal Applications, and Polysaccharides: Structural Diversity and Functional Versatility. He alsoauthored or coauthored more than 190 professional papers and book chapters in the fields of polymer and cellulose chemistry, polyfunctional initiators, and bioactive polymers and held 15 international patents. Professor Dumitriu received his BSc (1959) and MS (1961) in chemical engineering and his Ph.D. (1971) in macromolecular chemistry from the Polytechnic Institute of Jassy, Romania.

Valentin I. Popaearned his BSc and MSc in chemical engineering (1969) and Ph.D. in the field of polysaccharide chemistry (1976) from Polytechnic Institute of Iasi, Romania. He was awarded the Romanian Academy Prize for his contributions in the field of seaweed chemistry (1976). He has published more than 500 papers in the following fields: wood chemistry and biotechnology, biomass complex processing, biosynthesis and biodegradation of natural compounds, allelochemicals, bioadhesives, and bioremediation. Dr Popa is also the author or coauthor of 37 books or book chapters. He holds six patents and has been involved in many Romanian and European research projects as scientific manager. He is also a professor of wood chemistry and biotechnology at "Gheorghe Asachi" Technical University of Iasi, and editor-in-chief of Cellulose Chemistry and Technology.

Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Chemistry / General
TECHNOLOGY & ENGINEERING / Textiles & Polymers