Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.
Diffusion Controlled Systems: Polymeric Microcapsules (James C. Price). Diffusion Controlled Systems: Hydrogels (Richard Korsmeyer). Polymers for Enteric Coating Applications. (George A. Agyilirah and Gilbert Banker). Coacervation: Principles and Applications (David W. Newton). Polymerized Liposomes as Drug Carriers (Steven L. Regen). Bioadhesive Polymers and Drug Delivery (David A. Pecosky and Joseph R. Robinson). Synthetic Bioerodible Polymer Drug Delivery Systems (Kam W. Leong). Collagen-Based Drug Delivery Devices (Mou-Ying Fu Lu and Curt Thies). Acrylic Latex Systems (Kevin M. Scholsky, Peter J. Tarcha, and Ann Hsu). Poloxamers in the Pharmaceutical Industry (Irving Schmolka). Ion-Exchange Resin Delivery Systems (Saul Borodkin). Animal Testing of Polymer Based Systems (Kenneth R. Majors and Mitchell B. Friedman). Regulatory Requirements for New Drug Submissions (Frederick Gustafson and Richard Kiernan). Beyond Today's Technology (Peter J. Tarcha and R. Saul Levinson).