Presenting state-of-the-art research advancements, Porous Media: Applications in Biological Systems and Biotechnology explores innovative approaches to effectively apply existing porous media technologies to biomedical applications. In each peer-reviewed chapter, world-class scientists and engineers collaborate to address significant problems and discuss exciting research in biological systems.
The book begins with discussions on bioheat transfer equations for blood flows and surrounding biological tissue, the concept of electroporation, hydrodynamic modeling of tissue-engineered material, and the resistance of microbial biofilms to common modalities of antibiotic treatments. It examines how biofilms influence porous media hydrodynamics, describes the modeling of flow changes in cerebral aneurysms, and highlights recent advances in Lagrangian particles methods. The text also covers passive mass transport processes in cellular membranes and their biophysical implications, the modeling and treatment of mass transport through skin, the use of porous media in marine microbiology, the transport of large biological molecules in deforming tissues, and applications of magnetic stabilized beds for protein purification and adsorption, antibody removal, and more. The final chapters present potential in situ characterization techniques for studying porous media and conductive membranes and explain the development of bioconvection patterns generated by populations of gravitactic microorganisms in porous media.
Using a common nomenclature throughout and with contributions from top experts, this cohesive book illustrates the role of porous media in addressing some of the most challenging issues in biomedical engineering and biotechnology. The book contains sophisticated porous media models that can be used to improve the accuracy of modeling a variety of biological processes.
Table of Contents
A General Set of Bioheat Equations Based on the Volume Averaging Theory. Mathematical Models of Mass Transfer in Tissue for Molecular Medicine with Reversible Electroporation. Hydrodynamics in Porous Media with Applications to Tissue Engineering. Biomedical Implications of the Porosity of Microbial Biofilms. Influence of Biofilms on Porous Media Hydrodynamics. Using Porous Media Theory to Determine the Coil Volume Needed to Arrest Flow in Brain Aneurysms. Lagrangian Particle Methods for Biological Systems. Passive Mass Transport Processes in Cellular Membranes and Their Biophysical Implications. Skin Electroporation: Modeling Perspectives. Application of Porous Media Theories in Marine Biological Modeling. The Transport of Insulin-Like Growth Factor through Cartilage. Biotechnological and Biomedical Applications of Magnetically Stabilized and Fluidized Beds. In Situ Characterizations of Porous Media for Applications in Biofuel Cells: Issues and Challenges. Spatial Pattern Formation of Motile Microorganisms: From Gravitactic Bioconvection to Protozoan Culture Dynamics.
Kambiz Vafai is a professor of mechanical engineering at the University of California, Riverside. With over 4,000 ISI citations to his name, Dr. Vafai is the author or coauthor of more than 200 archival journal articles, thirteen book chapters, and eighteen symposium volumes as well as the editor of three books. He is also an editorial advisory board member of several journals and editor-in-chief of the Journal of Porous Media and Reviews in Porous Media — an International Journal. He has worked on a multitude of fundamental research investigations, a number of which have addressed some pertinent concepts presented for the first time.