Principles and Applications of Therapeutic Ultrasound in Healthcare: 1st Edition (Hardback) book cover

Principles and Applications of Therapeutic Ultrasound in Healthcare

1st Edition

By Yufeng Zhou

CRC Press

364 pages | 48 Color Illus. | 256 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9781466510272
pub: 2015-12-10
SAVE ~$33.00
$165.00
$132.00
x
eBook (VitalSource) : 9781466510296
pub: 2015-11-30
from $28.98


FREE Standard Shipping!

Description

Principles and Applications of Therapeutic Ultrasound in Healthcare introduces concepts, principles, construction, and applications of therapeutic ultrasound: from bench to bedside. A comprehensive examination of the industry and medical application of ultrasound therapy, this book highlights working principles, research progress, and system structures of therapeutic ultrasound. It describes the principles of therapeutic ultrasound, details the system construction, introduces current and emerging applications, and discusses developing therapeutic ultrasound technologies.

Divided into two parts, the book first introduces the fundamentals of biomedical acoustics, discusses ultrasound calibration methods, and the structures of available therapeutic ultrasound systems before moving on to the various applications of ultrasound therapy used in clinics. It includes a variety of extensive clinical trials, outcome photos and illustrating figures, and a critical commentary on the challenges in this field.

The author discusses topics that include:

  • The derivation of wave equation
  • The mathematical solution of the wave propagation
  • The phenomena of reflection
  • Refraction and transmission in the acoustic field from different acoustic sources
  • The radiation pattern of the ultrasound transducer
  • The acoustical properties of biological tissues
  • Ultrasound-induced bioeffects
  • Cavitation
  • The design of the ultrasound transducer
  • The characterization method of the produced acoustic field

An easy reference offering full coverage of popular ultrasound therapies, Principles and Applications of Therapeutic Ultrasound in Healthcare provides a simple explanation of fundamental acoustics, including wave equation, propagation, nonlinearity, and transducer design. It also discusses other potential applications, and is geared toward academia, industry, and researchers.

Table of Contents

Introduction

References

Wave Equation

Fundamental Equations for an Ideal Fluid

Small-Amplitude 1D Acoustic Wave Equation

3D Wave Equation

Velocity Potential

Speed of Sound

Acoustic Impedance

Solution of Wave Equation

Spherical Waves

Cylindrical Waves

Wave in Solid

Assignment

References

Sound Reflection, Refraction, and Transmission

Acoustic Energy and Intensity

Sound Pressure and Intensity Level

Boundary Conditions

Normal Incidence

Oblique Incidence

Middle Layer Transmission

Assignment

References

Acoustic Field and Wave Radiation

Acoustic Interference

Acoustic Wave Radiation

Transducer Field

Array Transducer Field

Assignment

References

Acoustical Properties of Biological Tissue

Cell and Tissue

Acoustic Attenuation

Wave Equation with Attenuation

Viscosity Relaxation

Attenuation Measurement

Assignment

References

Nonlinear Acoustics

D Nonlinear Dynamic Equation

Nonlinear Equation of State

Nonlinearity Parameters

Nonlinear Acoustic Wave Propagation

Interaction of Finite-Amplitude Sound Waves

Interaction of Sources at Different Frequencies

Propagation of Finite-Amplitude Wave in Viscous Medium

Measurement of Nonlinearity B/A

Assignment

References

Cavitation

Nucleation

Cavitation Threshold

Rectified Diffusion

Bubble Dynamics

Cavitation Effects

Cavitation Measurement

References

Transducer

Piezoelectricity

Equivalent Circuit

Transducer Design

Capacitive Transducer

Transducer Array

References

Acoustic Field Calibration and Measurement

Acoustic Pressure Measurement

Radiation Force Balance

Calorimeter

Holography

Interferometric Measurement

Field Mapping Using Vibrometer

Schlieren Imaging

Light Diffraction Tomography

Light Scanning of Ultrasound Field

Time-Delay Spectrometry

Infrared Thermography

References

Ultrasonic Physiotherapy

Introduction

System Structure and Treatment Protocol

Mechanisms and Bioeffects

Clinical Trials

Discussion

References

Hyperthermia

Rationale of Hyperthermia

Effect of Thermal Conduction and Blood Perfusion

Ultrasound Hyperthermia Technology

Thermometry

Treatment Planning and Control

Ultrasound Hyperthermia-Induced Effects

Clinical Outcome

Combination with Radiation

Hyperthermia-Mediated Drug Release

Future Work

References

Shock Wave Lithotripsy and Treatment

Kidney Stone Disease and SWL History

Development

Limitations in Renal Injury and Stone Fragmentation

Technology and Measurement

Mechanisms of SWL: Stone Fragmentation and Renal Injury

Technical Improvement

Shock Wave Therapy

References

High-Intensity Focused Ultrasound

Introduction

History of HIFU

Advantages of HIFU

System Structure and Operation

Mechanism of HIFU

HIFU Monitoring and Control

Clinical Applications

Clinical Experience

HIFU-Related Therapeutic Methods

Conclusions

References

Ultrasound-Mediated Drug Delivery/Gene Transfection

Introduction

Drug/Gene Delivery Approach

Acoustically Active Drug Vehicles

Sonoporation

Targeted Drug Delivery for Cancer

Gene Therapy

Sonophoresis

Sonothrombolysis

Drug Delivery across the Blood–Brain Barrier (BBB)

Sonodynamic Therapy

Discussion and Future Directions

References

Future of Therapeutic Ultrasound

About the Author

Yufeng Zhou is an assistant professor at the School of Mechanical & Aerospace Engineering at Nanyang Technological University, Singapore. He earned his BS and MS in electrical science and engineering from Nanjing University, China, in 1996 and 1999, respectively, and a PhD in mechanical engineering from Duke University, Durham, North Carolina, in 2003. Dr. Zhou’s research interests are focused on biomedical ultrasound, including ultrasound diagnosis (i.e., elastography) and therapy (i.e., shock wave lithotripsy to break calculus, high-intensity focused ultrasound for cancer ablation, ultrasound-mediated drug/gene delivery). He is a senior member of the Institute of Electrical and Electronics Engineers and an advisory editorial board member of the journal Ultrasound in Medicine and Biology.

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
MED080000
MEDICAL / Radiology & Nuclear Medicine
SCI055000
SCIENCE / Physics