Principles of Mucosal Immunology: 1st Edition (Paperback) book cover

Principles of Mucosal Immunology

1st Edition

By Society for Mucosal Immunology

Edited by Phillip D. Smith, Thomas T. MacDonald, Richard S. Blumberg

Garland Science

552 pages | 220 Color Illus.

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Paperback: 9780815344438
pub: 2012-04-18
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Principles of Mucosal Immunology is designed for graduate students and postdoctoral fellows, researchers in immunology and microbiology, and medical and dental students. It presents the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier—the gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems. Topics include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. Principles of Mucosal Immunology is sponsored by the Society for Mucosal Immunology and is written by internationally recognized leaders in the field.


"Principles of Mucosal Immunology is an excellent book and can be recommended not only to students and professionals that wish to expand their knowledge in immunology but to the tutors of specialized immunology courses too. Furthermore, it is very detailed and clear enough to become one of the first books you reach for whenever a basic question of immunology arises." - Scandinavian Journal of Immunology

“The length of the book is optimal, covering most areas of mucosal immunology, and the depth of coverage in each area is appropriately proportioned to the available literature in the field. The quality of the color figures and diagrams are excellent. Expert contributors are internationally recognized leaders in the field of mucosal immunology. Although it has multiple authors, there is uniformity of style. In comparing this book with other textbooks of mucosal immunology, Principles of Mucosal Immunology presents not opinions of particular authors, but collective expert opinions of the Society of Mucosal Immunology with a Board of Counselors established in guiding the development of this book’s content, ensuring that the latest paradigms were presented. Therefore, this book represents the most up-to-date and comprehensive mucosal immunology textbook available…Principles of Mucosal Immunology achieves the aim of providing a standard textbook for students of all levels interested in advanced training in mucosal immunology. The book is well organized and has downloadable figures and diagrams to facilitate instructors teaching in classroom settings.”

- Gastroenterology

Table of Contents

I. Development and Structure of Mucosal Tissue

1. Overview of the Mucosal Immune System Structure

2. Phylogeny of the Mucosal Immune System

3. Immunological and Functional Differences Among Individual Compartments of the Mucosal Immune System

4. Secreted Effectors of the Innate Mucosal Barrier

II. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis

5. Immune Function of Epithelial Cells

6. Intraepithelial Lymphocytes: Unusual T Cells at Epithelial Surfaces

7. Lymphocyte Populations within the Lamina Propria

8. Mucosal B Cells and Their Function

9. Secretory Immunoglobulins and Their Transport

10. Role of Dendritic Cells in Integrating Immune Responses to Lumenal Antigens

11. Intestinal Macrophages in Defense of the Mucosa

12. Mucosal Basophils, Mast Cells, and Eosinophils

13. M Cells and the Follicle-Associated Epithelium

14. Lymphocyte Trafficking from Inductive Sites to Effector Sites

15. Mucosal Tolerance

III. Microbial Commensalism

16. Recognition of Microbe-Associated Molecular Patterns by Pattern Recognition Receptors

17. The Commensal Micorbiota and Its Relationship to Homeostasis and Disease

IV. Genitourinary Tract

18. The Immune System of the Genitourinary Tract

19. Mucosal Immune Responses to Microbes in the Genitourinary Tract

V. Nose, Airways, Oral Cavity, and Eyes

20. Immunobiology of the Nose, Upper Airways, and Oral Cavity

21. Bronchial Associated Lymphoid Tissue and Immune-mediated Respiratory Diseases

22. The Ocular Surface as a Mucosal Immune Site

VI. Infectious Diseases of Mucosal Surfaces

23. Mucosal Interactions with Enteropathogenic Bacteria

24. Heliobacter pylori Infection

25. Viral Infections

26. Infection-driven Periodontal Disease

27. Vaccine Strategies for Mucosal Infections

VII. Specific Immune-mediated Diseases of Mucosal Surfaces

28. Celiac Disease

29. IgA Nephropathy

30. Mucosal Manifestations of Immunodeficiencies

31. Inflammatory Bowel Disease

32. Food Sensitive and Eosinophilic Enteropathies

About the Author/Editors

The Society for Mucosal Immunology advances research and education related to the field of mucosal immunology.

Phillip D. Smith, MD, is Professor of Medicine and Microbiology and The Mary J Bradford Professor of Gastroenterology, Department of Medicine at the University of Alabama at Birmingham, Alabama.

Thomas T. MacDonald, PhD, FRCPath, FMedSci, is Dean for Research and Professor of Immunology, Centre for Immunology and Infectious Disease, at Barts and the London School of Medicine and Dentistry, London.

Richard S. Blumberg, MD, is Professor of Medicine, Harvard Medical School, Chief, Gastroenterology and Hepatology Division, Brigham and Women’s Hospital, Boston, Massachusetts.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Immunology
SCIENCE / General
SCIENCE / Life Sciences / Biology / General
SCIENCE / Life Sciences / Cytology