Prolyl Hydroxylase, Protein Disulfide Isomerase and Other Structurally Related Proteins
Addressing the folding of proteins to natural states as well as cotranslational and post translational modifications that effect function, this work analyzes the function of specific enzymes in the complex processes of protein conformation, assembly and stability. It highlights up-to-date advances made in creating accurate protein folding for protein stability, offering results in understanding disease pathology and the development of better drugs.
Table of Contents
"Prolyl 4-Hydroxylase: An Overview, Norberto A. Guzman Prolyl 4-Hydroxylase Inhibitors, Volkmar Günzler and Klaus Weidmann Occurrence of Dihydroxyproline in Proteins and Peptides, Steven W. Taylor and J. Herbert Waite Distribution and Expression of Prolyl 4-Hydroxylase-Beta Subunit/Protein Disulfide Isomerase in Vertebrate Cells, William V. Everson and Winston W. Y. Kao Prolyl 4-Hydroxylase and Protein Disulfide Isomerase in Plants, Richard A. Dixon and Basil S. Shorrosh Protein Disulfide Isomerase from Soybean: Isolation, Structure, and Function in Protein Folding, Yukio Kawamura, Tetsuya Ookura, and Ken Kainuma Physiological Roles of the Thiol: Protein Disulfide Oxidoreductases, Jordan L. Holtzman HIP-70/GRP58/ERp61/PLC-Alpha/CPT: A Single Gene Product and Member of the Protein Disulfide Isomerase Gene Family with Thiol Oxidoreductase Activity Subject Neuroendocrine Regulation, Charles V. Mobbs, Michael Kaplitt, and Donald Pfaff Estrogen-Responsive Domain of Protein Disulfide Isomerase, Lois T. Hunt, John C. M. Tsibris, and William N. Spellacy Protein Disulfide Isomerase as a Novel Target for ATP, Eric Quéméneur The Thioredoxin System and Thioredoxin Domains of Protein Disulfide Isomerase from the Endoplasmic Reticulum, Johanna Lundström-Ljung and Arne Holmgren Chaperone Activity of Protein Disulfide Isomerase, Chih-chen Wang Protein Disulfide Isomerase and the Complications of Protein Folding, Hiram F. Gilbert The Peptide Binding Site of Protein Disulfide Isomerase, Robert Noiva, Sawako Onodera, Melissa D. Schwaller, and William A. Irwin Protein Disulfide Isomerase as a Component of Muscle Sarcoplasmic Reticulum, Shairaz Baksh, Marek Michalak, and Larry Fliegel Microsomal Triglyceride Transfer Protein: A Heterodimer Consisting of Protein Disulfide Isomerase and a Unique Large Subunit, John R. Wetterau Reductive Function of PDI at the Surface of Mammalian Cells: Its Role in Diphtheria Toxin Translocation and HIV Entry into Human Cells, Hugues J.-P. Ryser, Richard Mandel, Angelo Gallina, and Alicia Rivera Structural Analysis of the Beta Subunit of Prolyl 4-Hydroxylase, James A. Bassuk Retina Cognin: A Tissue-Specific PDI-Related Protein Involved in Cell Signaling, Robert E. Hausman, Johanna L. Phillips, Harold Pariser, Vered Holdengreber, and Yehuda Ben-Shaul Protein Disulfide Isomerase: A Putative Calcium Storage Protein in the Endoplasmic Reticulum, Benjamin Kaminer, Djamel Lebeche, and Héctor A. Lucero Protein Disulfide Isomerase: Cellular Enzymology of the CXXC Motif, Peter T. Chivers, Martha C. A. Laboissière, and Ronald T. Raines Protein Disulfide Isomerase: Use in the Production of Recombinant Pharmaceutical Proteins, Janet L. Wolfe "