The role of metal ions in protein folding and structure is a critical topic to a range of scientists in numerous fields, particularly those working in structural biology and bioinorganic chemistry, those studying protein folding and disease, and those involved in the molecular and cellular aspects of metals in biological systems. Protein Folding an
FOLDING AND STABILITY OF METALLOPROTEINS : Metal Ions, Protein Folding, and Conformational States: An Introduction. The Folding Mechanism of c-Type Cytochromes. The Mechanism of Cytochrome c Folding: Early Events and Kinetic Intermediates. Stability and Folding of Copper-Binding Proteins. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability. Folding and Stability of Myoglobins and Hemoglobins. MECHANISMS OF METAL TRANSPORTERS, AND ASSEMBLY: Frataxin: An Unusual Metal-Binding Protein in Search of a Function. Mechanism of Human Copper Transporter Wilson's Disease Protein. METAL IONS, PROTEIN CONFORMATION, AND DISEASE: a-Synuclein and Metals.Zinc and Misfolding. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease. METALLOPROTEIN DESIGN, SIMULATION, AND MODELS: Metallopeptides as Tools to Understand Metalloprotein Folding and Stability. The Folding Landscapes of Metalloproteins.