Protein Folds: A Distance-Based Approach, 1st Edition (Hardback) book cover

Protein Folds

A Distance-Based Approach, 1st Edition

By Henrik Bohr, Soren Brunak

CRC Press

336 pages

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Hardback: 9780849340093
pub: 1995-10-20
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Description

Written by outstanding scientists in physics and molecular biology, this book addresses the most recent advances in the analysis of the protein folding processes and protein structure determination. Emphasis is also placed on modelling and presentation of experimental results of structural membrane bound proteins.

Many color plates help to illustrate structural aspects covered including:

  • Defining folds of protein domains

  • Structure determination from sequence

  • Distance geometry

  • Lattice theories

  • Membrane proteins

  • Protein-Ligand interaction

  • Topological considerations

  • Docking onto receptors

    All analysis is presented with proven theory and experimentation.

    Protein Folds: A Distance-Based Approach is an excellent text/reference for biotechnologists and biochemists as well as graduate students studying in the research sciences.

  • Table of Contents

    Introduction, H. Bohr and S. Brunak

    Overview

    Three Paradoxes of Protein Folding, P.G. Wolynes

    Protein-Ligand Complexes and Protein Biosynthesis

    Conserved Water Molecules and Protein Folding in Fungal Peroxidases, S. Larsen and J.F.W. Petersen

    Interplay between Metal Coordination Geometry and Protein Structure, R. Bauer, M. Bjerrum, E. Danielsen, E. Friis, J.M. Hammerstad, L. Hemmingsen, M.V. Pedersen, and J. Ulstrup

    Elongation Factor Tu: A G-Protein in Protein Biosynthesis, P. Nissen, M. Kjeldgaard, S. Thirup, L. Reshetnikova, G. Polekhina, B.F.C. Clark and J. Nyborg

    Electron Transfer of the Di-Heme Protein: Pseudomonas stutzeri cytochrome c4, , J.-J. Karlsson, A. Kadziola, A. Rasmussen, T.E. Rostrup, and J. Ulstrup

    Profile Methods for Protein Structure and Fold Determination

    Sequence Matching in Homology Modelling, M. Gribskov

    Screening Genome Sequences for Known Folds, M. Braxenthaler and M.J. Sippl

    Protein Fold Determination Using a Small Number of Distance Restraints, A. Aszódi, M.J. Gradwell, and W.R. Taylor

    How Many Protein Fold Classes Are To Be Found?, P-A. Lindgård and H. Bohr

    Distance-Based Protein Structure Prediction and Evaluation

    The Effect of a Distance-Cutoff on the Performance of The Distance Matrix Error When Used as a Potential Function to Drive Conformational Search, S. Le Grand, A. Elofsson, and D. Eisenberg

    Protein Structure Prediction: How Self-Misleading Can Be Avoided, A. Ya. Badretdinov, A.M. Gutin, and A.V. Finkelstein

    Sequence Space Analysis: Identification of Functionally or Structurally Important Residues in Protein Sequence Families, G. Casari, C. Sander, and A. Valencia

    Fitting 1-D Predictions into 3-D Structures, B. Rost

    Determination of Membrane Bound Protein Structure and Function

    Modelling a-helical Integral Membrane Proteins, D. Donnelly and J.B.C. Findlay

    Use of Small Organic Compounds and Metal-ions as Structural and Functional Probes in 7TM Receptors, T.W. Schwartz, C.E. Elling, S.M. Nielsen, K. Thirstrup, S. Zoffmann, M. Rosenkilde, D. Marchal, R. den Hollander, U. Gether, and S.A. Hjorth

    Using Sequence Information and Model Building to Explore Subtype Specificity in GPCRs, R. Bywater, G. Vriend, L. Oliveira, and D. van Aalten

    Statistical Mechanics and Kinetics of Protein Folding Processes

    Proposed Rules of the Protein Folding Game, M. Crippen and V.N. Maiorov

    Protein Folding Studied by Monte Carlo Simulations, A. Sali, E. Shakhnovich, and M. Karplus

    Folding Kinetics of Protein Like Heteropolymers, N.D. Socci and J.N. Onuchic

    Energy Landscape and Folding Mechanisms in Proteins, Z. Guo and D. Thirumalai

    Topological Aspects of Protein Folds

    Resonator Driven Protein Folding: The Implication of Topology for Protein Structure and Folding, J. Bohr, H. Bohr, and S. Brunak

    Chirality in Protein Structure, T.W.F. Slidel and J.M. Thornton

    Packing within and between Subunits Defined by Internal Cavities, S.J. Hubbard and P. Argos

    Protein Modelling and Docking

    Modelling and Predicting a-helical Transmembrane Structures, W.R. Taylor and D.T. Jones

    HIV GP120 Docking Interactions and Inhibitor Design Based on an Atomic Structure Derived by Molecular Modelling Using the DREIDING II Force Field, J.L. Gabriel and W.M. Mitchell

    A Model of the 3D Structure of Obelin-The Photoprotein From Obelia longissima, T. Sandalova

    Index

    Subject Categories

    BISAC Subject Codes/Headings:
    MED008000
    MEDICAL / Biochemistry
    MED071000
    MEDICAL / Pharmacology
    SCI086000
    SCIENCE / Life Sciences / General