Proteins: Concepts in Biochemistry, 1st Edition (Paperback) book cover


Concepts in Biochemistry, 1st Edition

By Paulo Almeida

Garland Science

398 pages | 350 B/W Illus.

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Paperback: 9780815345022
pub: 2016-03-14
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Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function. Intended for a one-semester course in biochemistry or biophysical chemistry with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles.

Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first year graduate students, and practitioners in chemistry, biochemistry, biology, and biophysics.

Table of Contents

1.Statistical Thermodynamics of Biological Molecules

2.Protein Structure

3.Evolution of Protein Sequence and Structure

4.Protein Stability

5.Protein Folding

6.Binding, Allostery, and Cooperativity

7.Enzyme Kinetics

Appendix A. Calculation of the excess heat capacity curve of protein thermal denaturation

Appendix B. Calculation of the average helicity from the partition function

Appendix C. Solution of rate equations for two-state system

About the Author

Paulo Almeida is a Professor in the Department of Chemistry and Biochemistry at the University of North Carolina Wilmington. Prior to his academic appointment at UNCW, he was an Assistant Professor of Chemistry at the University of Coimbra and at the University of Algarve, Portugal. His research seeks to understand the mechanism of antimicrobial, cytolytic peptides, and cell-penetrating peptides, as well as study domain formation in lipid membranes in terms of the molecular interactions between lipids, and how they are influenced by proteins and peptides bound or incorporated into the membrane. Almeida is a member of the Editorial Board of Biophysical Journal, as well as a member of the Biophysical Society and American Chemical Society. Almeida has written several book chapters in addition to being an active reviewer for professional journals and author of numerous papers.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biochemistry
SCIENCE / Life Sciences / Biochemistry
SCIENCE / Chemistry / General
SCIENCE / Life Sciences / General