Proteins and Peptides: Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes, 1st Edition (Hardback) book cover

Proteins and Peptides

Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes, 1st Edition

Edited by Randall J. Mrsny, Ann Daugherty

CRC Press

288 pages | 70 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9781420078060
pub: 2009-10-19
$180.00
x
eBook (VitalSource) : 9780429144455
pub: 2009-10-19
from $28.98


FREE Standard Shipping!

Description

Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is an invaluable source for drug discovery and development scientists in the biopharmaceutical industry who frequently navigate the maze of protein and peptide pharmacokinetics, pharmacodynamics, and metabolism.

Key features include:

Table of Contents

In Vitro/In Vivo Correlations of Pharmacokinetics, Pharmacodynamics, and Metabolism for Hematologic Growth Factors and Cytokines

Graham Molineux and Stephen J. Szilvassy

In Vitro–In Vivo Correlations of Pharmacokinetics, Pharmacodynamics, and Metabolism for Antibody Therapeutics

C. Andrew Boswell, Rong Deng, Kedan Lin, Wendy S. Putnam, Cherry Lei, Frank-Peter Theil, Amita Joshi, Paul J. Fielder, and Leslie A. Khawli

In Vitro/In Vivo Correlations of Pharmacokinetics, Pharmacodynamics, and Metabolism for Extracellular Matrix–Binding Growth Factors

Matthew A. Nugent, Maria Mitsi, and Jean L. Spencer

Metabolic Processes at Injection Sites Affecting Pharmacokinetics, Pharmacodynamics, and Metabolism of Protein and Peptide Therapeutics

Randall J. Mrsny

Local Tissue Responses to Polymer Implants Affecting Pharmacokinetics, Pharmacodynamics, and Metabolism of Proteins and Peptides

James M. Anderson and William G. Brodbeck

Engineering as a Means to Improve the Pharmacokinetics of Injected Therapeutic Proteins

Mark S. Dennis, Yik A. Yeung, Henry B. Lowman, and Robert F. Kelley

Ophthalmic Delivery of Protein and Peptide Therapeutics; Pharmacokinetics, Pharmacodynamics, and Metabolism Considerations

Arto Urtti

Pharmacokinetic and Pharmacodynamic Aspects of Intranasal Delivery

Henry R. Costantino, Anthony P. Sileno, Mike Templin, Chingyuan Li, Diane Frank, Gordon C. Brandt, and Steven C. Quay

Oral Delivery of Protein and Peptide Therapeutics: PK/PD and Metabolism Considerations

Puchun Liu and Steven Dinh

Drug Interaction Studies of Therapeutic Biologics: Protein and Peptide Actions and Interactions That Alter Their Pharmacokinetics, Pharmacodynamics, and Metabolism

Iftekhar Mahmood

Intersection of Pharmacogenomics with Pharmacokinetics and Pharmacodynamics

Cecile M. Krejsa, Emmanuel Monnet, and David Cregut

About the Series

Drugs and the Pharmaceutical Sciences

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED071000
MEDICAL / Pharmacology
MED072000
MEDICAL / Pharmacy