Pulmonary Hypertension: 1st Edition (Hardback) book cover

Pulmonary Hypertension

1st Edition

Edited by Marc Humbert, Joseph P. Lynch

CRC Press

552 pages | 48 B/W Illus.

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Hardback: 9781420094756
pub: 2009-07-24
eBook (VitalSource) : 9780429147623
pub: 2009-07-24
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Written by internationally recognized experts, Pulmonary Hypertension bridges the gap between pulmonology and cardiology to provide clinicians in both disciplines with knowledge of the signs, symptoms, diagnosis, and pharmacologic and surgical treatments for pulmonary hypertension (PH). Through the use of clinical trials, this ground-breaking text supplies a comprehensive review of both the primary and secondary clinical and investigative aspects of this condition.

Discussing controversies and concepts in PH diagnosis and management, this guide explores:

  • classification and epidemiology, pathology, pathogenesis, genetics, and diagnosis of PH
  • causes of the condition, such as idiopathic pulmonary arterial hypertension (IPAH)
  • PAH-complicating connective tissue diseases (CTD), congenital heart diseases, human immunodeficiency virus (HIV), and other disorders
  • the mechanisms, toxicities, and efficacy of therapeutic agents
  • the role of combination therapies, novel agents, and future directions
  • PH in specific patient populations such as pregnant and critically-ill patients in the ICU

Table of Contents

Classification, Epidemiology, Pathology, Pathogenesis and Genetics

Updated Clinical Classification of Pulmonary Hypertension Ivan M. Robbins and Ge´rald Simonneau

Epidemiology of Pulmonary Arterial Hypertension Marc Humbert

Pathology of Pulmonary Hypertension Peter Dorfmu¨ ller

Pathogenesis of Pulmonary Hypertension Norbert F. Voelkel, Lori Sweeney, and Herman Bogaard

Animal Models of Pulmonary Hypertension Laurence Dewachter and Robert Naeije

Genetics of PAH Eric D. Austin, James E. Loyd, and John A. Phillips III

Imaging and Diagnosis of Pulmonary Hypertension

Imaging of Pulmonary Hypertension Dominique Musset and Sophie Maıˆtre

Echocardiography of Pulmonary Arterial Hypertension Adam Torbicki and Anna Fijałkowska

Diagnosis and Hemodynamic Assessment of Pulmonary Arterial Hypertension Rajan Saggar, Rajeev Saggar, John A. Belperio, David A. Zisman, Joseph P. Lynch III, and Jamil Aboulhosn

Clinical Variants of Pulmonary Hypertension

Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension Jerome Le Pavec and Marc Humbert

Pulmonary Arterial Hypertension Complicating Connective Tissue Diseases Paul M. Hassoun

Pulmonary Arterial Hypertension in Congenital Heart Disease Daniel S. Levi, Victoria Scott, and Jamil Aboulhosn

Pulmonary Arterial Hypertension and Human Immunodeficiency Virus Infection Bruno Degano and Olivier Sitbon

Portopulmonary Hypertension Michael J. Krowka

Pulmonary Hypertension Complicating Schistosomiasis Caio J. C. S. Fernandes, Carlos Jardim, and Roge´rio Souza

Pulmonary Hypertension in Sickle Cell Disease Mark T. Gladwin

Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis David Montani

Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease Emmanuel Weitzenblum and Ari Chaouat

Pulmonary Hypertension Complicating Interstitial Lung Disease David A. Zisman, John A. Belperio, Rajan Saggar, Rajeev Saggar, Michael C. Fishbein, and Joseph P. Lynch III

Pulmonary Hypertension in Chronic Mountain Sickness Dante Penaloza and Francisco Sime

Chronic Thromboembolic Pulmonary Hypertension William R. Auger and Peter F. Fedullo

Medical Treatment of Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension: Conventional Therapy Olivier Sitbon

Medical Treatment of PAH: Prostacyclins Paul R. Forfia and Vallerie V. McLaughlin

Phosphodiesterase Type 5 Inhibitors Nazzareno Galie`

Medical Treatment of Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists

Kristina Kemp and Marc Humbert

Medical Treatment of PAH: Combination Therapy, Novel Agents, Future Directions, and

Current Recommendations Lewis J. Rubin and Sean P. Gaine

Goal-Oriented Therapy in Pulmonary Arterial Hypertension Marius M. Hoeper

Atrioseptostomy and Surgery for Pulmonary Hypertension

Atrial Septostomy for the Treatment of Severe Pulmonary Hypertension Julio Sandoval, Jorge Gaspar, and Toma´s Pulido

Surgical Management of Pulmonary Hypertension Philippe G. Dartevelle, Elie Fadel, Sacha Mussot, Dominique Fabre, Olaf Mercier, Marc Humbert, and Ge´rald Simonneau

The Selection and Timing of Transplantation for Patients with Pulmonary Arterial Hypertension Paul A. Corris

Difficult Pulmonary Hypertension

Pulmonary Arterial Hypertension and Pregnancy Xavier Jai¨s, Laura Claire Price, Florence Parent, and Marc Humbert

Pediatric Pulmonary Hypertension Cecile Tissot and Maurice Beghetti

Practical Management of Pulmonary Arterial Hypertension in the Intensive Care Unit Benjamin Sztrymf and Marc Humbert

Endpoints and Clinical Trials

End Points and Clinical Trial Design in Pulmonary Arterial Hypertension: Clinical and Regulatory Perspectives Andrew J. Peacock


About the Series

Lung Biology in Health and Disease

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Cardiology
MEDICAL / Pulmonary & Thoracic Medicine