This book focuses on the advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and reproducibility. It also concentrates on the effective applications of these methods that resulted in many discoveries of the role of the proteins expressed in living cells and biological fluids. The first part of the book focuses on the description of advantages and disadvantages of each of the commonly used quantitative proteomic methods in terms of accuracy, sensitivity, and, especially, reproducibility. The second part of the book focuses on providing concise descriptions of the effective applications of these methods to demonstrate how they have resulted in many important discoveries of the roles of the proteins expressed in living cells.
Table of Contents
K. Imai, A. Koshiyama
Mass Spectrometry Utilizing ICAT
Proteomic Analyses of Post-translational Modifications
W.-C. Ku and Y.Ishihama
Cardiovascular Proteomic Analysis
T. Suzuki and R. Nagai
Proteome in Neurodegenerative Diseases
S. Shimohama, et al.
Liver Disease-Related Proteome
H. Uto, et al.
Respiratory Disease Related Proteome
M. Seike and A. Gemma
Renal Disease-Related Proteome
S. Kaname and T. Yamamoto
Phosphoproteomics of Tumor Cell Lines
HCV Infection and Mitochondria Proteomics
K. Moriya et al.
Infectious Disease by SELDI
P. R. Langford
Quantitative Proteomic Analysis of HIV Infection
L. J. Fu, S.F.Y. Li