Apple Academic Press
622 pages | 23 Color Illus. | 346 B/W Illus.
Volume 5 of the 5-volume Quantum Nanochemistry focuses on modeling and predicting of the enzyme kinetics and quantitative structure-activity relationships. It reveals the quantum implications to bio-organic and bio-inorganic systems, to enzyme kinetics, and to pharmacophore binding sites of chemical-biological interaction of molecules through cell membranes in targeting specific bindings modeled by celebrated QSARs (Quantitative Structure-Activity Relationships) here reshaped as Qu-SAR (Quantum Structure-Activity Relationships).
"[This book] is of vanguardist value, while offering analytical insight and control to QSAR modeling, by algebraic (inherently quantum) approach as an alternative to already classical statistical methods, while not being disjointed yet rather complementary to it, so highly contributing to the QSAR field toward offering a true theory of chemical-biological interactions and mechanisms. . . .Thus, I heartily recommend this book by Mihai V. Putz for its use and study equally for training of the freshman (including graduate and master students) in quantum eco-pharmaco-toxicity and QSAR as well by advanced researchers (as PhD students and post-docs) for modeling, ordering, and interpreting the chemical-biological data by the nano-structural (i.e. quantum nanochemical) causes of the biological activities as recorded (observable) effects."
—Mircea V. Diudea, Department of Organic Chemistry, Faculty of Chemistry and Chemical Engineering, Babes-Bolyai University of Cluj-Napoca, Romania (from the Foreword to Volume 5)
Preface. Foreword by Mircea V. Diudea, Babes-Bolyai University of Cluj-Napoca, Romania. Logistic Enzyme Kinetics. Statistical Space for Multivariate Correlations. Chemical Orthogonal Spaces for Structure-Activity Relationship (COS-SAR). Index.