Radioimmunotherapy of Cancer: 1st Edition (Hardback) book cover

Radioimmunotherapy of Cancer

1st Edition

By Paul G. Abrams, Alan R. Fritzberg

CRC Press

416 pages

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Hardback: 9780824702779
pub: 2000-07-11
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pub: 2000-07-11
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Reflecting the past 20 years of intense research in radioimmunotherapy, this timely reference surveys an expansive breadth of topics on the evolving developments in radiation therapy. Placed in the context of advances in cancer treatment, chapters progress systematically from basic principles and properties of radionuclides to detailed summaries of current cancer therapies.

Up to date, clearly organized, and thorough-sure to become a standard in the field!

Providing comprehensive treatment on radiolabeled antibody therapy, Radioimmunotherapy of Cancer

  • reviews dosimetric principles and clinical dosimetry of radioimmunotherapy in the targeting and delivery of radiation

  • describes tumor architectures and outlines novel constructs for radionuclide delivery

  • analyzes a variety of improved targeting approaches, including pretargeting contextual analysis of extracorporeal techniques in radioimmunotherapy

  • details studies from the radiotherapy of lymphoma, solid tumors, and ovarian cancer and the targeted radiotherapy of neuroblastoma and squamous head and neck cancer

  • and much more!

    With contributions from nearly 50 international experts and containing over 1300 literature references, drawings, photographs, tables, and equations, Radioimmunotherapy of Cancer is an invaluable and indispensable reference for physicians in nuclear medicine and medical physicists; oncologists, radiologists, radiochemists, and radiopharmacists; immunologists, pulmonologists, and cancer researchers; pharmacologists and drug delivery pharmaceutical chemists; and upper-level undergraduate, graduate, and medical school students in these disciplines.

  • Reviews


    From the Foreword…

    The past two decades have provided an opportunity for investigators to explore the capacity of monoclonal antibodies and other targeting molecules to deliver therapeutic doses of radiation via radioisotope conjugates. This book assembles a strong cast of these investigators to review the progress that has been made and to clarify the challenges that remain.

    "-Albert F. Lobuglio, M.D.

    Director, Comprehensive Cancer Center

    Associate Dean, School of Medicine

    Evalina B. Spencer Professor of Oncology

    University of Alabama at Birmingham

    …a clear, complete and outstanding report of the current status of radioimunotherapy….

    …highly recommended to nuclear medicine residents, but it also serves a solid review of radioimmunotherapy for physicians who have been in this field for many years.

    -Tijdschrift voor Nucleaire Geneeskunde, 2000

    "…collects different contributions from the most important investigators in the field….

    …important….very sharp and interesting.

    "-Minerva Medica

    Table of Contents

    Radionuclides for Radioimmunotherapy

    Dosimetric Principles of Targeted Radiotherapy

    Joseph A. O'Donoghue

    Radionuclide Dosimetry and Radioimmunotherapy of Cancer

    Ruby F. Meredith, Donald J. Buchsbaum, and Susan J. Knox

    Metallic Radionuclides for Radioimmunotherapy

    Alan R. Fritzberg and Claude F. Meares

    Radiohalogens for Radioimmunotherapy

    Michael R. Zalutsky

    Delivery of Radiation to Tumors

    Tumor Architecture and Targeted Delivery

    Harold F. Dvorak, Janice A. Nagy, Dian Feng, and Ann M. Dvorak

    Antibodies and Novel Constructs for Tumor Targeting

    Dale C. Slavin-Chiorini, Patricia Horan Hand, and John W. Greiner

    Pretargeted Radioimmunotherapy of Cancer

    Marco Chinol, Chiara Grana, Roberto Gennari, Marta Cremonesi, J. G. Geraghty, and Giovanni Paganelli

    Evolution of a Pretarget Radioimmunotherapeutic Regimen

    Louis J. Theodore, Alan R. Fritzberg, Jody E. Schultz, and Donald B. Axworthy

    Extracorporeal Techniques in Radioimmunotherapy

    Sven-Erik Strand, Jan G. Tennvall, Hans-Olov Sjögren, JianQing Chen, Michael Garkavij, Cecilia Hindorf, Rune Nilsson, and Bengt E. B. Sandberg

    Targeted Radiotherapy of Cancer

    Radioimmunotherapy in the Treatment of Non-Hodgkin's Lymphoma

    Monica S. Krieger, Paul L. Weiden, O. Press, G. L. DeNardo, and Hazel B. Breitz

    Radioimmunotherapy of Solid Tumors

    Hazel B. Breitz, Paul L. Weiden, and Paul L. Beaumier

    Intraperitoneal Radioimmunotherapy of Ovarian Cancer

    Konstantinos N. Syrigos and Agamemnon A. Epenetos

    Targeted Radiotherapy in the Treatment of Osteosarcoma: Radiobiological Basis, Clinical Status, and Future Prospects

    Øyvind S. Bruland and Alexander Pihl

    Targeted Radiotherapy of Neuroblastoma

    Cornelis A. Hoefnagel

    Targeted Radiotherapy of Squamous Head and Neck

    Guus A. M. S. van Dongen, Frank B. van Gog, Ruud H. Brakenhoff, Jasper J. Quak, Remco de Bree, Gerard W. M. Visser, and Gordon B. Snow

    Subject Categories

    BISAC Subject Codes/Headings:
    MEDICAL / Oncology