Understand Quantitative Radiobiology from a Radiation Biophysics PerspectiveIn the field of radiobiology, the linear-quadratic (LQ) equation has become the standard for defining radiation-induced cell killing. Radiotherapy Treatment Planning: Linear-Quadratic Radiobiology describes tumor cell inactivation from a radiation physics perspective and of
Introduction. The Generation of Quantitative Radiobiology Data. Intrinsic Radiosensitivity of Proliferating and Quiescent Cells. Effects of Ionization Density and Volume. Impact of Fraction Size, Dose-Rate, Temperature and Overall Treatment Time on Tumor Cell Response. Ionizing Events, Molecular Targets and Lethal Lesions. The Radiosensitivity of Tumor Cells In Vitro versus In Vivo. Modern Radiobiology and the LQ Equation. Normal Tissues Radiobiology. Radiobiology Applied to Tumor Response Modeling. Epilogue. References. Index.