Receptor Binding Radiotracers: 1st Edition (e-Book) book cover

Receptor Binding Radiotracers

1st Edition

Edited by William C. Eckelman

CRC Press

192 pages

Purchasing Options:$ = USD
Hardback: 9780367259631
pub: 2019-07-22
SAVE ~$39.80
$199.00
$159.20
x
eBook (VitalSource) : 9780429290794
pub: 2019-07-17
from $32.50


FREE Standard Shipping!

Description

First Published in 1982, this book explores the role of receptor-binding radiotracers. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of radiology, and other practitioners in their respective fields.

Table of Contents

Volume I.

SECTION I: BIOCHEMICAL BASIS FOR RECEPTOR-BINDING RADIOTRACERS.

Introduction. 1. Receptor Binding Studies: General Considerations. 2. Identification of Receptors In Vitro. 3. Localizing Drug and Neurotransmitter Receptors in Vivo with Tritium-Labeled Tracers.

SECTION II: RADIOPHARMACEUTICAL CHEMISTRY OF RECEPTOR-BINDING RADIOTRACERS.

Introduction. 4. Production of High Specific Activity Compounds with Short-Lived Radionuclides. 5. Radiolabeled Adrenergic and Musearinic Blockers for In Vivo Studies. 6. In Vivo and In Vitro Steroid Receptor Assays in the Design of Estrogen Radiopharmaceuticals. 7. Radiolabeled Enzyme Inhibitors. 8. Radioiodinated Cholesterol as a Radiotracer in Biochemical Studies. Index.

Volume II.

Introduction. 1. Application of Modeling Principles to Receptor-Binding Radiotracers. 2. Pharmacokinetic Aspects of the In vivo, Noninvasive Study of Neuroreceptors in Man. 3. A Complimentary Radiopharmaceutical and Mathematical Model by Pharmacokinetic Modeling. 4. Separating Changes in Flow from Changes in Receptor Binding by Pharmacokinetic Modeling.

SECTION IV: INSTRUMENTATION FOR RECEPTOR-BINDING RADIOTRACERS.

Introduction. 5. Simulated Uptake Ratio Requirements for Spherical Lesions Imaged with a Conventional Scintillation Camera. 6. Potential of Longitudinal Tomography for Imaging Receptor-Binding Radiotracers. 7. Emission Tomography-Detection of Single Photons with Multidetector Devices and Rotating Gamma Cameras. 8. Instrumentation for Quantitative Tomographic Determination of Concentrations of Positron-Emitting, Receptor-Binding Radiotracers.

SECTION V: CLINICL RELEVANCE OF RECEPTOR-BINDING RADIOTRACRES.

Introduction: The Role of Receptors in Disease. 9. Quantitative Changes in Receptor Concentrations as a Function of Disease. Index.

About the Editor

William C. Eckelman

About the Series

Routledge Revivals

Are there elusive titles that you need and have been trying to source for years but thought that you would never be able to find?

Well this may be the end of your quest – here is a fantastic opportunity for you to discover past brilliance and purchase previously out of print and unavailable titles by some of the world’s most eminent academic scholars.

Drawing from over 100 years of innovative, cutting-edge publishing, Routledge Revivals is an exciting programme whereby key titles from the distinguished and extensive backlist of the many acclaimed imprints associated with Routledge will be re-issued.

The programme draws upon the illustrious backlists of Kegan Paul, Trench & Trubner, Routledge & Kegan Paul, Methuen, Allen & Unwin and Routledge itself.

Routledge Revivals spans the whole of the Humanities and Social Sciences, and includes works by some of the world’s greatest thinkers including Emile Durkheim, Max Weber, Simone Weil, Martin Buber, Karl Jaspers and Max Beloff.

If you are interested in Revivals in the Behavioral Sciences, please visit https://www.routledge.com/series/PSYREVIVALS

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED000000
MEDICAL / General
MED080000
MEDICAL / Radiology & Nuclear Medicine