Recurrent Pregnancy Loss: Causes, Controversies, and Treatment, Second Edition, 2nd Edition (Hardback) book cover

Recurrent Pregnancy Loss

Causes, Controversies, and Treatment, Second Edition, 2nd Edition

Edited by Howard J. A. Carp, Howard Carp

CRC Press

456 pages | 60 B/W Illus.

Purchasing Options:$ = USD
Hardback: 9781482216141
pub: 2014-12-10
$170.00
x
eBook (VitalSource) : 9780429169991
pub: 2014-12-10
from $28.98


FREE Standard Shipping!

Description

Recurrent pregnancy loss presents a vexing clinical problem primarily for medical professionals treating patients in reproductive medicine and in maternal-fetal medicine. However, with its numerous causes and various suggested treatment options, the problem is more multidisciplinary in nature, involving gynecology, genetics, endocrinology, immunology, pediatrics, and internal medicine. Exploring basic science and clinical applications, the second edition of the bestselling text Recurrent Pregnancy Loss: Causes, Controversies, and Treatment provides an authoritative and comprehensive update on advances in the understanding and management of this troubling phenomenon.

The book covers basic scientific topics such as genetics and cytokines and profiles major advances in immunology, endocrinology, and thrombotic mechanism. It discusses the methodology of clinical research and the application of evidence-based medicine to clinical practice. It also reviews various late obstetric complications, along with issues caused by extreme prematurity and possible resulting handicaps. This second edition presents new material on the latest controversies, featuring opinions from both sides of ongoing debates. It includes new chapters on autoimmunity, third party reproduction, the use of immunostimulants such as CSF, and Chinese medicine.

Designed for specialists working in reproductive medicine clinics and those involved with maternal-fetal care, the book is also ideal for generalists and gynaecologists seeking a comprehensive view of developments in the field.

Table of Contents

The Epidemiology of Recurrent Pregnancy Loss; Ole B. Christiansen

Signaling between Embryo and Mother in Early Pregnancy: Basis for Development of Tolerance; Eytan R. Barnea

Genetics of Spontaneous Abortions; Joe Leigh Simpson

Debate: Should Fetal Karyotyping be Performed in Recurrent Pregnancy Loss? Yes; Howard J. A. Carp

Debate: Should Fetal Karyotyping be Performed in Recurrent Pregnancy Loss? No; Zvi Borochowitz

Debate: Should Preimplantation Genetic Screening be Performed in Recurrent Pregnancy Loss? Yes; Pere Mir, Nasser Al-Asmar, Lorena Rodrigo, Carlos Simon, and Carmen Rubio

Debate: Should Preimplantation Genetic Screening or Preimplantation Genetic Diagnosis be Performed in Recurrent Pregnancy Loss? No; Anna M. Musters and Mariette Goddijn

Debate: Screening for Chromosomal Aberrations in Recurrent Pregnancy Loss: Nonspecific Testing is Sufficient; Howard Cuckle

Debate: Screening for Chromosomal Aberrations in Recurrent Pregnancy Loss: Noninvasive Prenatal Testing, Cytogenetics and Ultrasound are Needed; Peter Benn

Does the Maternal Immune System Regulate the Embryo’s Response to External Toxins? Arkady Torchinsky, Vladimir Toder, Shoshana Savion, and Howard J. A. Carp

Fetal Structural Malformations—Embryoscopy; Thomas Philipp

Fetal Structural Malformations—Ultrasound; Akhila Vasudeva and Pratap Kumar

Endocrinology of Pregnancy Loss; N. Pluchino, P. Drakopoulos, J. M. Wenger, S. Luisi, M. Russo, and A. R. Genazzani

Debate: Should Progesterone Supplements be Used? Yes; Jerome H. Check

Debate: Should Progesterone Supplements be Used? No; Aisha Hameed, Shazia Malik, and Lesley Regan

Opinion: Progestogens in Recurrent Miscarriage; Howard J. A. Carp

Debate: Should Human Chorionic Gonadotropin Supplementation be Used? Yes; James Walker

Debate: Should Human Chorionic Gonadotropin Supplementation be Used? No; Harish M. Bhandari and Siobhan Quenby

Antiphospholipid Syndrome—Pathophysiology; Rotem Inbar, Miri Blank, and Yehuda Shoenfeld

Diagnosis of Antiphospholipid Antibody-Associated Abortions; Marighoula Varla-Leftherioti

Management of Antiphospholipid Syndrome in Pregnancy; Alana B. Levine and Michael D. Lockshin

Defects in Coagulation Factors Leading to Recurrent Pregnancy Loss; Aida Inbal and Howard J. A. Carp

Debate: Should Thromboprophylaxis be Used in Hereditary Thrombophilias with Recurrent Pregnancy Loss? Yes; Benjamin Brenner

Debate: Should Thromboprophylaxis be Used in Hereditary Thrombophilias with Recurrent Pregnancy Loss? No; Pelle G. Lindqvist

Opinion: Can Recurrent Pregnancy Loss be Prevented by Antithrombotic Agents? Howard J. A. Carp

Uterine Anomalies and Recurrent Pregnancy Loss; Daniel S. Seidman and Mordechai Goldenberg

The Immunobiology of Recurrent Miscarriage; Marighoula Varla-Leftherioti

Debate: Should Immunotherapy be Used? Lymphocyte Immunization Therapy: Yes; Edward E. Winger and Jane L. Reed

Debate: Should Immunotherapy be Used? Intravenous Immunoglobulin: Yes; Carolyn B. Coulam

Debate: Should Immunotherapy be Used? Granulocyte colony stimulating factor: Yes; Fabio Scarpellini and Marco Sbracia

Debate: Should Immunotherapy be Used? No; Raj Rai

Autoimmunity and Recurrent Pregnancy Loss; Sonia Zatti, Andrea Lojacono, and Angela Tincani

Infections and Recurrent Pregnancy Loss; David Alan Viniker

The Male Factor in Recurrent Pregnancy Loss and Embryo Implantation Failure; Richard Bronson

Midtrimester Loss: The Role of Cerclage and Pessaries; Israel Hendler and Howard J. A. Carp

Midtrimester Loss and Viability; Flora Y. Wong and Victor Y. H. Yu

Obstetric Outcomes after Recurrent Miscarriage; Howard J. A. Carp

Coping with Repeated Pregnancy Loss: Psychological Mechanisms; Keren Shakhar

Methodological Issues in Evidence-Based Evaluation of Treatment for Recurrent Miscarriage; Salim Daya

Investigation Protocol for Recurrent Pregnancy Loss; Howard J. A. Carp

A New Algorithm for Evaluation and Treatment of Recurrent Pregnancy Loss; William H. Kutteh, Raymond W. Ke, and Paul R. Brezina

Third Party Reproduction in Recurrent Pregnancy Loss; Gautam N. Allahbadia and Rubina Merchant

"Slippery Fetus": Recurrent Pregnancy Loss in Traditional Chinese Medicine; Aviv Messinger and Keren Sela

A Patient’s Perspective; Mindy Gross

Epilogue; Howard J. A. Carp

Index

About the Editors

Prof. Carp studied Medicine at Charing Cross Hospital Medical School in London. He completed his training for the MRCOG in the UK. He has since worked at the Sheba Medical Center, Tel Hashomer, in Israel, and has held a Senior Lecturer post in Embryology at Tel Aviv University. He is Professor of Obstetrics and Gynaecology at Tel Aviv University. He has many clinical interests, including ectopic pregnancy, implantation, and infertility. He has edited two other books: The Infertility Manual and Principles and Practice of Assisted Reproductive Technology. Another book, Progestogens in Gynecological Practice is in press. He has published over 70 original research articles, 16 review articles and 6 chapters in books and has been invited to lecture in many parts of the world. Prof. Carp has taken a special interest in recurrent miscarriage, other forms of pregnancy loss, and infertility in general.

About the Series

Series in Maternal-Fetal Medicine

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MED029000
MEDICAL / Family & General Practice
MED033000
MEDICAL / Gynecology & Obstetrics
MED082000
MEDICAL / Reproductive Medicine & Technology