1st Edition

Regulation of Sleep and Circadian Rhythms


 
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Book Description

Providing an up-to-date overview of the field, this state-of-the-art reference details how sleep and circadian rhythms are interconnected, revealing the impact of various disease states on, and the molecular and genetic basis for, disrupted sleep and circadian rhythmicity and their effects on physical and mental health, safety, performance, and productivity.
Integrates current and rapidly advancing discoveries of sleep and circadian rhythms!
Offering an integrative approach to research findings from basic science to clinical points of view, Regulation of Sleep and Circadian Rhythms discusses

  • the three developmental stages of sleep in mammals
  • the evolution of circadian timing
  • brainstem regulation of sleep
  • non-REM sleep and thalamocortical function
  • cognitive correlates of behavioral states
  • dysfunctional sleep
  • sleep homeostasis
  • neuroanatomy of circadian control
  • acute effects of light
  • organization of vertebrate circadian timing systems
  • production, sites, and mechanisms of melatonin
  • genetic aspects of pathological human sleep
  • sleep alterations associated with age, disease, and psychiatric state
  • and more!
    Complete with over 3200 references, tables, and figures, Regulation of Sleep and Circadian Rhythms is an essential resource for clinical neurologists and neurobiologists, pulmonologists, psychiatrists and behavioral scientists, endocrinologists and neuroendocrinologists, chronobiologists, sleep specialists, general medicine practitioners and internists, gerontologists, psychologists, and graduate and medical school students in these disciplines.
  • Table of Contents

    Introduction to Sleep and Circadian Rhythms, Phyllis C. Zee and Fred W. Turek
    Ontogeny of Sleep and Circadian Rhythms, Fred C. Davis, Marcos G. Frank, and H. Craig Heller
    Neural Control of Sleep, J. Allan Hobson
    Circadian and Homeostatic Control of Wakefulness and Sleep, Derk-Jan Dijk and Dale M. Edgar
    Influence of Light on Circadian Rhythmicity in Humans, Charles A. Czeisler and Kenneth P. Wright, Jr.
    Role of Melatonin in the Regulation of Sleep, Fred W. Turek and Charles A. Czeisler
    Melatonin and Circadian Rhythmicity in Vertebrates: Physiological Roles and Pharmacological Effects, David R. Weaver
    The Impact of Changes in Nightlength (Scotoperiod) on Human Sleep, Thomas A. Wehr
    Cellular and Molecular Mechanisms of Sleep, Tarja Porkka-Heiskanen and Dag Stenberg
    Cellular and Molecular Mechanisms of Circadian Rhythms in Mammals, Piotr Zlomanczuk and William J. Schwartz
    Molecular and Genetic Aspects of Sleep, Thomas S. Kilduff and Emmanuel Mignot
    Molecular Genetic Approaches to the Identity and Function of Circadian Clock Genes, Jonathan P. Wisor and Joseph S. Takahashi
    Circadian and Sleep Control of Hormonal Secretions, Eve Van Cauter and Karine Spiegel
    Relationships Between Sleep and Immune Function, James M. Krueger, Jidong Fang, and Rachael A. Floyd
    Intrinsic Disruption of Normal Sleep and Circadian Patterns, Scott S. Campbell
    Sleep and Circadian Rhythm Disorders in Aging and Dementia, Donald L. Bliwise
    Effects of Sleep and Circadian Rhythms on Performance, Julie Carrier and Timothy H. Monk
    Neurological Disorders Associated with Disturbed Sleep and Circadian Rhythms, Phyllis C. Zee and Zoran M. Grujic
    Psychiatric Disorders Associated with Disturbed Sleep and Circadian Rhythms, Daniel J. Buysse, Eric A. Nofzinger, Matcheri S. Keshavan, Charles F. Reynolds III, and David J. Kupfer

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