This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of retinoid therapy, this source also addresses topics outside of dermatology, such as vitamin A nutrition, and the role of antioxidants in aging, metabolic activation, and cellular signaling. With chapters by internationally recognized authorities in specialties ranging from biochemistry and nutrition to molecular biology and clinical science, this source will stand as the only up-to-date source on the topic.
Table of Contents
From Carotenoids and Vitamin A to Retinoids. Animal Models for Retinoid Receptor Research. Retinoids and the Skin. Recent Studies on the Pharmacokinetics and Metabolism of Retinoids in the Skin. Anti-Aging Effects of Retinoids and Mechanisms of Action. Retinoid Therapy of Acne and Sebocyte-Related Disorders. Retinoids and Retinoic Acid Blocking Agents in Psoriasis. Retinoid Treatment of the Disorders of Cornfication. Oral Retinoid Therapy in Children and Infants. Retinoids in Cutaneous T-Cell Lymphomas. Retinoid Therapy and Autoimmune Skin Disease. Retinoids in the Prevention and Treatment of Skin Cancer. Side-Effects and Pitfalls in Retinoid Therapy. Retinoid-Induced Hyperlipidemia and the Risk of Atherosclerosis. Carotenoids and the Skin. Antioxidative Effects of Carotenoids. Beta-Carotene in the Treatment of Skin Disorders. Caroteinoids as Cancer Preventive Agents. Beta-Carotene in Erythropoietic Protoporphyria.
”…an excellent comprehensive reference on virtually all the effects, functions, and therapeutic applications of retinoids and skin…I would highly recommend it for all dermatologists since everyone uses retinoids in their practice…This is the best book I have read on the complexity of retinoids and their immunologic powers on the skin. Readers have to be prepared to spend time studying it, but they will be well rewarded.”