Reversal of Multidrug Resistance in Cancer  book cover
1st Edition

Reversal of Multidrug Resistance in Cancer

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ISBN 9780849347443
Published December 6, 1993 by CRC Press
160 Pages

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Book Description

This critical, state-of-the-art review brings together the scattered and often controversial information on multidrug resistance reversal. Leading scientists in the field cover P-glycoprotein, the genetics of resistance, and its reversal by drugs. Resistance modifiers and modulators are tabulated and critically evaluated. Reversal of Multidrug Resistance in Cancer is important reading for oncologists, cancer chemotherapists, and other cancer researchers.

Table of Contents

Preface (J.A. Kellen). The Phenomenon of Multidrug Resistance (J.A. Kellen). Collateral Sensitization in Multidrug Resistance (J.L. Biedler and B.A. Spengler). Cytogenetics of Multidrug Resistance (R. Ganapathi, D. Grabowski, and G. Hoeltge). Mathematical Models of Multidrug Resistance (J. Goldie, A.J. Coldman, and A. Lai). Multidrug Resistance in Human Malignancies (J.A. Kellen). Reversal of Multidrug Resistance (D. Fan, P.J. Beltran, and C.A. O'Brian). Outlook (J.A. Kellen and D. Fan). Conclusion (J.A. Kellen). Index.

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