Reversibility of Chronic Disease and Hypersensitivity, Volume 3: Clinical Environmental Manifestations of the Neurocardiovascular Systems, 1st Edition (Hardback) book cover

Reversibility of Chronic Disease and Hypersensitivity, Volume 3

Clinical Environmental Manifestations of the Neurocardiovascular Systems, 1st Edition

By William J. Rea, Kalpana Patel

CRC Press

413 pages | 98 B/W Illus.

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pub: 2014-09-26
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Description

Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 3: Environmental Manifestations of the Neurocardiovascular Systems draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, neurological, and cardiovascular systems with a special focus on vascular dysfunction and heart failure treatment.

The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction. It covers a wide variety of topics including environmental sensitivity due to external pollutants, environmental control for reducing total body load, pollutant damage to vascular perfusion, altered blood volume, fluctuations of oxygen extraction, effects of endocrine on the vascular system, effects of pollutants on myocardial cells, and mechanisms in vascular damage.

The book also discusses in detail a wide variety of clinical manifestations including vasculitis, cardiac arrhythmias, cardiac metabolic syndrome, myocarditis, atherosclerosis, heart failure, urticaria, and anaphylaxis. Treatment for heart failure is also discussed. The third volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.

Table of Contents

INTEGRATION OF THE MUSCULOSKELETAL AND NEUROLOGICAL SYSTEMS

Introduction

Entry of Environmental Pollutants: External and Internal Mechanisms of the Total Body Pollutant Load

External Pollutants

Internal Excitotoxins

Environmental Control for Reducing Total Body Load

ECU Construction and Maintenance

Use of the ECU

Summary

VASCULAR FUNCTION AND DYSFUNCTION

Introduction to the Cardiovascular System in Chemical Sensitivity

Physiology and Pollutant Damage to Vascular Perfusion: Changes in the Sympathetic Nervous System Function

Physiology of Vascular Perfusion

Autonomic Nervous System

Connective Tissue

Endothelins

Vascular Injury due to Pollutants

Neovascularization

Regional Perfusion Injury

Blood Volume

Effects of Pollutants on the Clotting System

Oxygen Extraction

Effects of Pollutants on Myocardial Cells

Types of Mechanisms in Vascular Damage

Nonimmune Mechanisms

Immune Mechanisms

Effects of Endocrine on the Vascular System

Pollutant Entry in Dyshomeostasis: Clinical Syndromes

Vasculitis

Small Vessel Vasculitis

Large Vessel Vasculitis

Hypersensitive Vasculitis

Eosinophilic Vasculitis

Recurrent Phlebitis

Cardiac Arrhythmias and Dysfunction

Sudden Cardiac Death

Hereditary Angioedema

Urticaria

Anaphylaxis

Cardiac Metabolic Syndrome

Cardiomyopathy

Myocarditis

Atherosclerosis

Environmental Aspects of Atherosclerosis

Cardiac Events and Hospital Admission

Changes in Heart Rate and Cardiac Function

Influence of Particulates

Pathophysiology Leading to Inflammation

Inflammation Mechanism

Myocardial Necrosis and Toxic Infarction

Cardioprotection

Apoptosis

Toxic Infarction

Triggering Agents of CAD

Heart Failure

Introduction

Heart Failure Pathology and Cell Communication

Heart Failure Pathophysiology

Energy-Starvation Hypothesis

Heart Failure Treatment

Classic Medical Treatment

Neural Humeral Activation

Emerging Therapeutic Options: Nutrients

Summary

Index

About the Authors

William J. Rea is a thoracic, cardiovascular, and general surgeon with an added interest in the environmental aspects of health and disease. He received his MD from The Ohio State University and was chief of thoracic surgery at the Veteran’s Hospital in Dallas. He has lectured on cardiovascular and thoracic surgery at the University of Texas S.W. Medical School and on environmental sciences at the University of Texas. Dr. Rea served on the board of the American Academy of Environmental Medicine and is currently a board member of the American Board of Environmental Medicine. Dr. Rea is a fellow of the American Academy of Environmental Medicine, the American College of Surgeons, and the Royal Society of Medicine. He was part of the team who resuscitated Governor John Connally when President Kennedy was shot.

Kalpana D. Patel is a pediatrician with an added interest in the environmental aspects of health and disease. She serves as an assistant professor of pediatrics at the State University of New York at Buffalo. Dr. Patel was awarded the Jonathan Forman Gold Medal Award for outstanding research in environmental medicine and the Herbert J. Rinkel Award for outstanding teaching by the American Academy of Environmental Medicine. Dr. Patel has served as president of the American Board of Environmental Medicine and is currently a member of its executive committee. She has also served on the board of the American Academy of Environmental Medicine and is a diplomate of both the American Board of Pediatrics and the American Board of Environmental Medicine. Dr. Patel is a fellow of the American Academy of Environmental Medicine.

Subject Categories

BISAC Subject Codes/Headings:
MED008000
MEDICAL / Biochemistry
MED045000
MEDICAL / Internal Medicine
SCI013000
SCIENCE / Chemistry / General
SCI026000
SCIENCE / Environmental Science