This book covers all aspects of gastrointestinal tract problems caused by alcohol misuse. Opening chapters discuss epidemiology and the metabolism of alcohol and the liver's role in that process. Alcohol and acetaldehyde dehydrogenases, free radicals, and endocrine changes are discussed in detail.
Table of Contents
1. The Extent of the Problems and the Epidemiological Aspects of Alcohol Drinking 2. The Metabolism of Alcohol and Its Implication for the Pathogenesis of Disease 3. Alcohol and Aldehyde Dehydrogenases in the Gastrointestinal Tract 4. Free Radicals and Ethanol Toxicity 5. Endocrine Changes in Alcoholism with Special Reference to Gastrointestinal Hormones 6. The Physiology of Digestion, Absorption and Metabolism in the Human Intestine 7. The Effects of Ethanol on Salivary Glands 8. Gastric Cytoprotection and Adaptation to Ethanol 9. Alcoholic Pancreatitis10. Small Bowel Injury by Ethanol 11. Alcohol-Induced Malabsorption of the Gastrointestinal Tract 12. Alcohol and Small Intestinal Permeability 13. Gastrointestinal Motility Disorders Induced by Ethanol 14. Protein Syntheses in the Gastrointestinal Tract and the Effect of Ethanol 15. Cell Turnover in the Gastrointestinal Tract and the Effect of Ethanol Helmut K. 16. Lipid Metabolism in the Intestinal Tract and Its Modification by 17. Alcohol’s Promotion of Gastrointestinal Carcinogenesis 18. Ethanol and the Gastrointestinal Tract: Mechanisms in Disease. Nutritional Implications of Hepatointestinal Disorders 19. Objectives for Future Research in understanding the Effects of Ethanol on the Gastrointestinal Tract. Index
Victor R. Preedy is a lecturer in the Department of Clinical Biochmistry, King's College School of Medicine and Dentistry, London. He also holds Honorary Appointments in The Roehampton Institute, the School of Pharmacy and the Persistent Viral Disease Research Foundation.
Ronald R. Watson, Ph.D., initiatied and directed the National Institure of Alcohol Abuse and Alcoholism (NIAAA) Alcohol Research Center at the University of Arizona College of Medicine. The main goal of the Center was to understand the role of ethanol-induced immunosuppression onimmune function and disease resistance in animals.