1st Edition

Revival: Cellular Immune Mechanisms and Tumor Dormancy (1992)

ISBN 9781138557826
Published January 28, 2019 by CRC Press
378 Pages

USD $68.95

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Book Description

Cellular Immune Mechanisms and Tumor Dormancy features the work of internationally recognized experts from various disciplines as they discuss the phenomenon of tumor dormancy in humans. Animal models are described in which cellular and molecular components of the immune control of dormancy have been identified, and the relevance of these models to human cancer patients is recognized. Data derived from studies of organ transplantation, adjuvant chemotherapy, radiotherapy, anaesthesia, surgery, and whole blood transfusion is presented to show the vulnerability of cellular mechanisms maintaining dormancy. The potential for increasing the incidence of dormancy in micro metastases is also shown for non-small cell lung cancer, lymphoma, and leukemia. Cellular Immune Mechanisms and Tumor Dormancy is an important reference volume that will benefit researchers from many disciplines, including immunologists, pathologists, surgeons, and clinicians

Table of Contents

An overview of mechanisms responsible for tumor dormancy / E. Frederick Wheelock --
A pathologist's view of tumor dormancy / Raymond Yesner --
Dormancy in experimental solid tumor systems / Duzanne A. Eccles --
Immune regulation of a murine T-cell lymphoma dormant state / E. Frederick Wheelock, Guchen Yang and Lieping Chen --
Idiotypic vaccination against B-cell lymphoma leads to dormant tumor / F.K. Stevenson ... [et al.)--Tumor dormancy in a murine B-cell lymphoma / Jonathan W. Uhr, Thomas Tucker and Ellen S. Vitetta --
Induction of tumor dormancy in BALB/c mice against non-immunogenic B-cell leukemia / Shimon Slavin ... [et al.)--Graft-versus-leukemia effect of allogeneic bone marrow transplantation: clinical and experimental aspects of late leukemia relapses / Robert L. Truitt ... [et al.)--Anesthesia and immune response / G.C. Moudgil and D.P. Singal --
Anesthesia, surgery, immune suppression, and tumor growth / Joel Lundy ... [et al.)--Blood transfusion and tumor growth: studies in animal models / D.P. Singal, S. Shirwadkar and M.A. Blajchman. (cont) The effect of perioperative blood transfusion on the outcome of cancer surgery / Paul I. Tartter --
Adjuvant treatment of non-small-cell lung cancer: a meta-analysis / T.H.M. Stewart and S. Raman --
The effect of renal transplantation in patients with a history of curative cancer therapy / Israel Penn --
Abnormal immunoregulation and the tumor dormant state in human cancer / Jules E. Harris and Donald P. Braun --
Soluble tumor antigens used in clinical trials of immunotherapy / Ariel C. Hollinshead --
Evidence for tumor dormancy in patients with non-small-cell lung cancer / T.H.M. Stewart and S. Raman --
Meta-analysis of clinical trials of specific immunotherapy of non-small-cell lung cancer / S. Raman and T.H.M. Stewart

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