A vast literature exists dealing with trace metals and a number of outstanding monographs deal with the biological, biochemical, or clinical effects of a specific trace metal or trace metals in general. However, newer aspects of trace metal research, i.e. the developmental aspects and generic implications, have not been systematically discussed in any existing texts. The present two volumes will summarize the present status of research in these areas and serve as milestones for future development in these areas of trace metal research.
Table of Contents
1. Introduction 2. Metal Ions and Nucleic Acid Structure 3. Metal Ions and DNA, RNA and Protein Synthesis 4. Some Consequences of Metal Effects on Disease and Aging 5. Concluding Remarks References
Owen M. Rennert, M.D., is Professor and Head of the Department of Pediatrics, Chief of the Section of Generics, Endocrinology, and Metabolism, Professor, Department of Biochemistry and Molecular Biology, and Director of the Program in Human Genetics in the Departments of Biochemistry and Molecular Biology at Pediatrics at the University of Oklahoma Health Sciences Center, Oklahoma City. Dr. Rennert is also Chief of the Pediatric Service of the Oklahoma Children’s Memorial Hospital, Oklahoma City.
Wai-Yee Chan, Ph.D., is an Associate Professor in the Department of Pediatrics and the Department of Biochemistry and Molecular Biology at the University of Oklahoma Health Sciences Center, Oklahoma City. He is also Co-Scientific Director, Trace Metals Laboratory of the State of Oklahoma Teaching Hospitals, and a Consultant in Medical Service to the Veteran’s Administration Medical Center, Oklahoma City.