Revival: Molecular Basis of Aging (1995): 1st Edition (Paperback) book cover

Revival: Molecular Basis of Aging (1995)

1st Edition

By Alvaro Macieira-Coelho

CRC Press

576 pages

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Using a new, integrative approach, Molecular Basis of Aging describes the aging phenomenon within mammalian organisms from the perspective of changes in information storage and coordination between hierarchical orders of structure. This unique approach provides the reader with a thorough insight into the evolution of molecular, cellular, tissue, and organ systems and processes in mammals. This informative volume contains up-to-date reviews of:

Table of Contents

The Storage of Information

Genome Reorganization of Mitotic Cells, A. Macieira-Coelho

Genomic Instability During Aging of Postmitotic Mammalian Cells, J.W. Gaubatz

DNA Repair During Aging, H. Niedermüller

Changes in Gene Expression During Aging of Mammals, M.S. Kanungo

Role of Mitochondria in Cell Aging, J. Miquel

The Flow of Information

Modifications of the Cell Surface Leading to Cell Elimination, H.U. Lutz

Protein Kinase C Signal Transmission During Aging, F. Battaini, S. Govoni, and M. Trabucchi

Changes in Transmembrane Signaling Mechanisms During Aging, Cellular and Molecular Aspects, A. Miyamoto and G. Roth

Structural Changes Modifying the Intracellular Flow of Information, A. Macieira-Coelho

The Aging of the Neuronal Cytoskeleton, P. Klosen and P. van den Bosch de Aguilar

Transport of mRNA into the Cytoplasm, W.E.G. Müller, G. Lauc, P.S. Agutter, and H.C. Schröder

Translational and Posttranslational Modifications During Aging, S.I.S. Rattan

Carbonyl Toxification Hypothesis of Biological Aging, D. Yin and U.T. Brunk

Amyloidosis and Aging, B. Westermark and K.H. Johnson

Extracellular Matrix, L. Robert and J. Labat-Robert

Brain Metabolism During Aging, S. Hoyer

Central Neurotransmission in the Elderly, H. Allain and D. Bentué-Ferrer

Age-Related Changes in Neuropeptidergic Neurons in the Human Hypothalamus, J.-N. Zhou and D.F. Swaab

About the Authors

Dr. Alvaro Macieira-Coelho is a Research Director at the French National Institute of Health. He received an MD from the University of Lisbon, Portugal, and a Ph.D. from the University of Uppsala Sweden.

About the Series

CRC Press Revivals

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Anatomy
MEDICAL / Biochemistry
MEDICAL / Geriatrics