This Monograph brings together within one cover the current knowledge about tumors of the nasal passages in man, in domestic and nondomestic animals. and in the rodents which are commonly employed in carcinogenesis studies in the laboratory.
Table of Contents
1. Nasal Airway Anatomy and Inhalation Deposition in Experimental Animals and People 2. The Pathogenesis of Nasal Neoplasia Induced by Alkylating and Aldehyde Compounds 3. Nitrosamine-Induced Nasal Cavity Carcinogenesis 4. Experimental Nasal Cavity Tumors Induced by Tobacco-Specific Nitrosamines 5. Histopathology of the Nasal Cavity in Laboratory Animals Exposed to Cigarette Smoke and Other Irritants 6. Radiation-Induced Nasal Cavity Tumors in Animals 7. Nasal Cavity Cancer in Laboratory Animal Bioassays of Environmental Compounds 8. Epstein-Barr virus and Nasopharyngeal Carcinoma 9. Studies on the Relationship between Epstein-Barr (Virus (EBV) and Nasopharyngeal Carcinoma (NPC) in China 10. Nasal Cavity Carcinogens: Possible Routes of Metabolic Activation 11. Metabolism of N-Nitrosames by the Nasal Mucosa 12. Summary and Conclusions Index
Gerd Reznik, D. V. M., Ph.D., is Directory of the Institute for Pathology and Toxicology, Byk-Gulden Pharmaceuticals in Hamburg, Germany.
Sherman F. Stinson, Ph.D., is an experimental pathologist currently affiliated with the Labotatory of Experimental Pathology of the National Cancer Institute, Frederick Cancer Research Facility, Frederick, Md.