Present classification schemes of bladder neoplasms are based on structural analyses of histologic material, primarily at the light microscopic level. Attempts to identify histologic variables of certain bladder lesions as biologic precursors of malignancy are in progress. Efforts to relate functional attributes of altered bladder tissues to preneoplastic and neoplastic structural changes are in active development. These advances do require a common recognition and communication of histologic patterns that are used as standard benchmarks.
This volume is offered to present in detail description of histologic characteristics of bladder cancer in humans and animals. Areas of recent research advances that may extend our knowledge of the pathobiology of bladder cancer are emphasized. Observations derived from experimental animals are related to the pathogenesis of bladder cancer in humans. This book is intended for pathologists, urologists, oncologists, radiation therapists, epidemiologists, environmental scientists, toxicologists, public health scientists, and regulatory officials.
Table of Contents
Pathology of Experimental Bladder Cancer in Rodents
The Ultrastructure and Pathobiology of Urinary Bladder Cancer
Scanning Electron Microscopy of the Lower Urinary Tract
Tissue Culture and Transplantation of Bladder
The Biological Characteristics of Continuous Cell Lines Derived from Human Bladder
George T. Bryan, M.D., Ph.D., is Professor of Human Oncology at the University of Wisconsin Center for Health Sciences, and Clinical Consultant, William S. Middleton Veterans Administration Hospital at Madison, Wisconsin.
Samuel M. Cohen, M.D., Ph.D., is a Professor and Vice-Chairman of the Department of Pathology and Laboratory Medicine and Professor of the Eppley Institute for research in Cancer and Allied Diseases at the University of Nebraska Medical Center in Omaha, Nebraska.