1st Edition

Revival: Tumor Matrix Biology (1995)

ISBN 9781138562844
Published January 25, 2019 by CRC Press
256 Pages

USD $59.95

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Book Description

This book would like to present the latest findings on different aspects of tumor matrix formation in connection with the tumor progression and metastasis and on alterations in the cellular components of tumor stroma during tumor demarcation and invasion. The contributors shed new light on the relationship between tumor cells and their extracellular microenvironment as well as on the mechanisms of fibrin/fibronectin network formation characteristics in tumors. These reviews provide insights into the formation and organization of tumor matrix during growth and metastasis and also offerthe possibility of learning to interfere with the metastatic cascade by manipulation of adhesion, coagulation and/or fibrinolytic events.

Table of Contents

Chapter 1

Immunohistochemical Characterizaion of Extracellular Matrix in Tumor Tissue

Chapter 2

Differential Expression of Proteogycans on the Surface of Malignant Cells and in the Tumor Stroma

Chapter 3

Overproduction of Hyaluronan in the Tumor Stroma

Chapter 4

Differential Expression of Fibronectin and its Degradation Products in Malignant Tumors

Chapter 5

Role of Tenascin in Cancer Development

Chapter 6

Composition of the Extracellular Matrix in Human Gliomas

Chapter 7

Integrin Expression in Tumor Progression -- Role of Signaling Mechanisms

Chapter 8

Tumor-Associated Macrophages and Their Modulatory Role in Tumor Progression

Chapter 9

The Coagulation-Cancer Interaction in Situ

Chapter 10

Intratumoral Fibrin Formation

Chapter 11

Modulation of Tumor Matrix by Components of the Plasminogen-Plasmin System

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Roza Adany, M.D., Ph.D., D.Sc.  is Professor of Hygiene and Epidemiology at University School of Medicine Debrecen, Hungary.