1st Edition

Schizophrenia The Final Frontier - A Festschrift for Robin M. Murray

Edited By Anthony S. David, Shitij Kapur, Peter McGuffin Copyright 2011
    424 Pages 9 Color & 32 B/W Illustrations
    by Psychology Press

    424 Pages 9 Color & 32 B/W Illustrations
    by Psychology Press

    Schizophrenia is a unique project reflecting the contribution that Robin M. Murray has made to the field of psychiatry over the past 35 years, with a particular focus on the advances that have been made to the understanding and treatment of schizophrenia.

    International contributors have been brought together to pay tribute to Robin Murray’s work and explore the latest findings in the area. Sections cover:

    • neurodevelopment
    • neuroscience and pharmacology
    • neuroimaging
    • genetics
    • cognition
    • social psychiatry
    • treatment.

    This book will be essential reading for psychiatrists, clinical psychologists, social and basic scientists whose work is related to major mental illness, as well as admirers of the work of Robin Murray.

    Weinberger, Foreword. Part I: Development. Karlsgodt, Ellman, Sun, Mittal, Cannon, The Neurodevelopmental Hypothesis of Schizophrenia. Laurens, Hodgins, Taylor, Murray, Is Earlier Intervention for Schizophrenia Possible? Identifying Antecedents of Schizophrenia in Children Aged 9–12 Years. Allin, Nosarti, The Black Hole of the Adolescent Brain. Jones, Miettunen, Suvisaari, Haukka, Isohanni, The Contribution of Nordic Populations, Registers and Scientists to the Search for the Causes of Schizophrenia and Other Psychiatric Disorders. Part II: Neuroscience. Morrison, The Search for Madness, A Metaphasical Trip Through the Basal Ganglia. Shaikh, Bramon, Neurophysiological Endophenotypes for Psychosis. Harrison, Glutamate, GABA and Solar Transmitter Systems: The Neuropathology of Amino-acids in Schizophrenia. Robbins, Animal Models of Schizophrenia Revisited. Part III: Neuroimaging. McGuire, Applications of Neuroimaging to the Study of Psychosis. Bullmore, Brain Networks and Schizophrenia. Dazzan, Morgan, Lappin, Fearon, Neuroimaging and Psychosis: Are Brain Changes in Individuals with Psychosis Neurodevelopmental for Some and Progressive for Others? Keshavan, Bhojraj, Gray Matter Alterations in Schizophrenia: Are They Reversible? Part IV: Genetics. McGuffin, A Short (and Partial) History of Genetics at the Institute of Psychiatry. Porteous, From First Contact to the Final Frontier: A Star Trek Along the DISC1 Pathway to Schizophrenia. Nimgaonkar, Chowdari, Prasad, Watson, Mansour, Wood, Lopez, Dopamine Gene Variants and Schizophrenia: A Scheme for Investigating Nominally Significant or Discrepant Associations. Crow, Ebb and Flow in Biological Psychiatry. Part V: Cognition. Garety, Freeman, Jolley, Ross, Waller, Dunn, Cognitive Models of Psychosis: The Jumping to Conclusions Reasoning Bias and Improving Psychological Treatment for Delusions. MacCabe, Giftedness and Psychosis. Part VI: Social Psychiatry. Bebbington, Towards a Social Aetiology of Psychosis: The Case of Child Sex Abuse. Boydell, Allerdyce, Does Urban Density Matter? Di Forti, Paparelli, Casadio, Skunk is Conquering UK: Does Higher Potency Cannabis Mean Higher Risk for Psychosis? C. Morgan, Hutchinson, Dazzan, K. Morgan, Fearon, The Social Determinants of Psychosis in Migrant and Minority Ethnic Populations. Mondelli, Pariante, Stress and Psychosis, Professor Murray's Contribution (so far) to the Vulnerability-stress Model. Van Os, Rutten, Van Winkel, Wichers, Chasing Gene-environment Interactions Across the Psychiatric Universe. Part VII: Treatment. Natesan, Kapur, How Antipsychotics Work: Examining Trans-synaptic Realities. Nicholson, Castle, Metabolic Disturbance and Schizophrenia. Lewis, Clinical Trials and Schizophrenia. Howes, What Does New Evidence Tell Us About Dopamine's Role in Schizophrenia? David, Robin M. Murray: A Bibliographical Note.


    Anthony S. David is professor of cognitive neuropsychiatry at the Institute of Psychiatry, King's College, London.

    Shitij Kapur is professor of schizophrenia, imaging and therapeutics, and Dean of School at the Institute of Psychiatry, King's College, London.

    Peter McGuffin is professor of psychiatric genetics at the Institute of Psychiatry, King's College, London.

    'We would not be here without the work of Professor Murray and we would not be heading towards an optimistic future of important breakthroughs in schizophrenia research were it not for his influence on the next generation of scientists and clinicians'Daniel R. Weinberger, from the foreword.