Stressing a structure-function approach, this multidisciplinary reference presents a detailed overview of the biological, chemical, physical, molecular and genetic tools and techniques utilized in the study of the skin barrier. It illustrates the impact of irritative skin reactions, as well as genetic and immune-mediated disease on hair and nail composition and formation.
Table of Contents
Introduction: similarities and differences between hair, nail and skin, Bo Forslind and, Magnus Lindberg. Skin: structure and function of the skin barrier - an introduction, Magnus Lindberg and Bo Forslind; lipid phase behaviour - a basis for an understanding of membrane structure and function, Emma Sparr and Sven Engstrom; biophysical analysis of lipid structure, David Moore, Jenifer Thewalt and Neil Kitson; confidence Intervals for the true lipid composition of the human skin barrier, Philip Wertz and Lars Norlen; stratum corneum lipid organization in vitro and in vivo as assessed by diffraction methods, Gonneke S.K. Pilgram and Joke A. Bouwstra; the mammalian skin barrier - structure, function and formation considerations, Lars Norlen; skin morphology in a species-related context, Gopinathan Menon; skin barrier function in normal and diseased skin, Anders Boman and Magnus Lindberg; understanding the irritative reaction, Carolyn Willis and Magnus Lindberg. Hair: hair growth and structure - an introduction, Magnus Lindberg and Bo Forslind; the hair fibre surface, Leslie N. Jones; biology of hair pigmentation, Desmond J. Tobin; androgen influence on hair growth, Valerie Randall; alopecia areata - an update on aetiology and pathogenesis, Andrew J.G. McDonagh, Rachid Tazi-Ahnini and Andrew G Messenger. Nail: nail anatomy, Structure and Function - morphogenesis and differentiation of the nail, David deBerker and Bo Forslin.
"…This interesting book provides and up to date review on structure and function of skin, hair and nail, presenting the last multidisciplinary results existing in this area of cutaneous research."
-Journal of Applied Cosmetology
"…their book will stimulate and direct further research… …a very strong basic science book that will be useful fo those researchers studying hair, skin, and nails."
---Doody's Electronic Journal