2nd Edition

Sleep Apnea
Pathogenesis, Diagnosis and Treatment




ISBN 9780849396977
Published November 11, 2011 by CRC Press
558 Pages - 187 B/W Illustrations

USD $290.00

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Book Description

Sleep apnea is a common chronic condition affecting millions of people. Written by a multidisciplinary team including sleep medicine specialists, pulmonologists, scientists, psychiatrists, otorhinolaryngologists, and more, this text provides essential scientific and clinical information for those treating and researching the condition.

Since the previous edition published, sleep medicine has become a fully formed medical speciality. This second edition has been expanded to contain more clinically relevant information regarding diagnosis and treatment, and includes:

  • New developments regarding the cardiovascular effects of sleep apnea
  • New developments regarding the role of sleep apnea in insulin resistance
  • Developing research on intermittent hypoxia in the disorder
  • Latest pharmacotherapeutic trials, addressed in the last chapter

Organized into sections and subsections to make the book easier for the reader to use, this essential text also examines sleep apnea in special populations, such as children, older adults or pregnant women, and takes into account gender differences in the disorder.

Table of Contents

PATHOGENESIS OF APNEA
Anatomy/biomechanics
Pathogenesis of obstructive sleep apnea: Insights from upper airway imaging studies, Murtuza M. Ahmed and Richard J. Schwab
Biomechanics of the upper airway during sleep, Philip L. Smith, Jason P. Kirkness, Susheel Patil, Hartmut Schneider, and Alan R. Schwartz
Neural mechanisms
Sleep-induced breathing instability, Ailiang Xie, Curtis A. Smith, and Jerome A. Dempsey
Mechanisms of upper airway hypotonia, Leszek Kubin and Richard O. Davies
Autonomic consequences of arousal from sleep and neural mechanisms of arousal, Richard L. Horner

GENETICS
Studies in humans
Airway reflexes: Changes with sleep, David P. White
Gender differences in sleep-disordered breathing, M. Safwan Badr and Jason H. Mateika

PATHOGENESIS OF CONSEQUENCES OF APNEA
Sleepiness
Mechanisms of sleepiness in obstructive sleep apnea, Mark S. Aloia and J. Todd Arnedt
Neuroimaging studies in obstructive sleep apnea, Liat Ayalon and Sean P. A. Drummond
Biomarkers and obstructive sleep apnea, Erna Sif Arnardottir, Bernie Sunwoo, and Allan I. Pack
Cardiovascular consequences

Obstructive sleep apnea and hypertension: Interactions and clinical implications, Suraj Kapa, Apoor S. Gami, and Virend K. Somers
Other cardiovascular consequences of sleep apnea, Julio A. Chirinos, Frederick F. Samaha, and Mark H. Sanders
Endocrine
Neuroendocrine aspects of sleep apnea, Brendon J. Yee, Peter Y. Liu, Craig Phillips, and Ronald R. Grunstein
Obstructive sleep apnea and glucose metabolism, Jan Polak, Brock A. Beamer, and Naresh M. Punjabi
Intermittent hypoxia
Intermittent hypoxia and neurocognitive function, David Gozal, Leila Kheirandish-Gozal, Yang Wang, and Shelley X. L. Zhang
Obstructive sleep apnea: Mechanisms of intermittent hypoxemia neural injury, Sigrid C. Veasey
Diagnosis of sleep apnea
Screening for sleep apnea, Indira Gurubhagavatula
Alternative strategies for diagnosis of patients with obstructive sleep apnea, Samuel T. Kuna

Sleep apnea in specialized groups
Obstructive sleep apnea: Children versus adults, Eliot S. Katz and Carole L. Marcus
Sleep apnea in older adults, Nalaka S. Gooneratne
Obstructive sleep apnea in pregnancy and menopause, Grace W. Pien
Treatment of sleep apnea
Adherence to CPAP treatment and functional status in adult obstructive sleep apnea, Terri E. Weaver, Judith Reishtein, and Amy M. Sawyer
CPAP therapy: Results of randomized controlled trials in obstructive sleep apnea, Sophie D. West and John R. Stradling
Oral appliance therapy for snoring and sleep apnea, Peter A. Cistulli and Ali M. Darendeliler
Upper airway surgery for obstructive sleep apnea, Edward M. Weaver and Andrew N. Goldberg|
Pharmacotherapeutic trials for sleep-disordered breathing, Jan Hedner, Ludger Grote, and Ding Zou

Index 551

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