1st Edition

Solid-Phase Extraction Principles, Techniques, and Applications

By Nigel J.K. Simpson Copyright 2000
    528 Pages
    by CRC Press

    Demonstrating the relationship of the basic theory of solid-phase extraction (SPE) to chromatography, this comprehensive reference illustrates how SPE techniques significantly contribute to the preparation of samples for a wide variety of analytical techniques. It provides step-by-step details on the applications of SPE to environmental matrices, broad-spectrum drug screening, veterinary drug abuse, pharmaceutical drug development, biological samples, and high-throughput screening. Written by world-renowned experts in the field, the book contains helpful reference charts, tables of solvent properties, selectivities, molecular acid/base properties, and more.

    Introduction to Solid-Phase Extraction, N.J.K. Simpson and M.J.M. Wells
    SPE Sorbents and Formats, J.J. Pesek and M.T. Matyska
    The Sample Matrix and Its Influence on Method Development, N.J. K. Simpson and P.M. Wynne
    Handling Large Volume Samples: Applications of SPE to Environmental Matrices, M.J.M. Wells
    SPE Technology 150; Principles and Practical Consequences, M. Henry
    Theory Meets Practice, C.F. Poole and S.K. Poole
    Secondary Interactions and Mixed-mode Extraction, B. Law
    Solid-Phase Extraction for Broad-Spectrum Drug Screening in Toxicological Analysis, R.A. de Zeeuw
    The Application of SPE to Veterinary Drug Abuse, P.M. Wynne
    Solid Phase Extraction of Biological Samples, S.H. Ingwersen
    Solid Phase Extraction Mediated by Covalent Bonding: Applications of Immobilized Phenylboronic Acid, I. D. Wilson and P. Martin
    Immuno-Affinity Extraction, D. Stevenson, B.A.A. Rashid, and S.J. Shahtaheri
    Matrix Solid Phase Dispersion (MSPD), S.A. Barker
    Automation of Solid Phase Extraction, L. Dordan
    Integration of SPE with the Analytical Technique, Part I - Liquid Chromatography, N.J.K. Simpson
    Integration of SPE with the Analytical Technique, Part II, N.J.K. Simpson
    Concluding Thoughts - New Directions for SPE, N.J. K. Simpson

    Appendix 1: A Summary of Common Matrix Properties and Components, N.J.K. Simpson
    Appendix 2: A Comparison Between Solid Phase Extraction and Other Sample Processing Techniques, N.J.K. Simpson
    Appendix 3: Ion Exchange Extraction, N.J.K. Simpson
    Appendix 4: A Summary of Current Suppliers of SPE Automation Equipment, N.J.K. Simpson

    Biography

    Nigel J.K. Simpson