Statistical Methods in Drug Combination Studies: 1st Edition (e-Book) book cover

Statistical Methods in Drug Combination Studies

1st Edition

Edited by Wei Zhao, Harry Yang

Chapman and Hall/CRC

240 pages

Purchasing Options:$ = USD
Hardback: 9781482216745
pub: 2014-12-19
eBook (VitalSource) : 9780429170539
pub: 2014-12-19
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The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. Howeve

Table of Contents

Drug Combination: Much Promise and Many Hurdles. Drug Combination Synergy. Drug Combination Design Strategies. Confidence Interval for Interaction Index. Two-Stage Response Surface Approaches to Modeling Drug Interaction. A Bayesian Industry Approach to Phase I Combination Trials in Oncology. Statistical Methodology for Evaluating Combination Therapy in Clinical Trials. Challenges and Opportunities in Analysis of Drug Combination Clinical Trial Data. Software and Tools to Analyze Drug Combination Data.

Subject Categories

BISAC Subject Codes/Headings:
MATHEMATICS / Probability & Statistics / General
MEDICAL / Pharmacology
MEDICAL / Pharmacy