Statistical and Computational Pharmacogenomics: 1st Edition (e-Book) book cover

Statistical and Computational Pharmacogenomics

1st Edition

By Rongling Wu, Min Lin

Chapman and Hall/CRC

368 pages

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Hardback: 9781584888284
pub: 2008-08-08
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pub: 2008-08-08
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Due to the tremendous accumulation of data for genetic markers, pharmacogenomics, the study of the functions and interactions of all genes in the overall variability of drug response, is one of the hottest areas of research in biomedical science. Statistical and Computational Pharmacogenomics presents recent developments in statistical metho

Table of Contents

Designs and Strategies for Genomic Mapping and

Haplotyping. Genetic Haplotyping in Natural Populations. Genetic Haplotyping in Experimental Crosses. A General Genetic Model for Genetic Haplotyping. Basic Principle of Functional Mapping. Functional Mapping of Pharmacokinetics and Pharmacodynamics. Haplotyping Drug Response With a Pharmacokinetics-Pharmacodynamics. Link Model. Functional Mapping of Biological Clocks. Genetic Mapping of Allometric Scaling. Functional Mapping of Drug Response with Allometric Scaling. Joint Functional Mapping of Drug Efficacy and Toxicity. Modeling Epistatic Interactions in Drug Response. Mapping Genotype-Environment Interactions in Drug Response. Nonparametric Functional Mapping of Drug Response

Semiparametric Functional Mapping of Drug Response. Author Index.

Subject Index.

Subject Categories

BISAC Subject Codes/Headings:
MATHEMATICS / Probability & Statistics / General