Due to the tremendous accumulation of data for genetic markers, pharmacogenomics, the study of the functions and interactions of all genes in the overall variability of drug response, is one of the hottest areas of research in biomedical science. Statistical and Computational Pharmacogenomics presents recent developments in statistical metho
Designs and Strategies for Genomic Mapping and
Haplotyping. Genetic Haplotyping in Natural Populations. Genetic Haplotyping in Experimental Crosses. A General Genetic Model for Genetic Haplotyping. Basic Principle of Functional Mapping. Functional Mapping of Pharmacokinetics and Pharmacodynamics. Haplotyping Drug Response With a Pharmacokinetics-Pharmacodynamics. Link Model. Functional Mapping of Biological Clocks. Genetic Mapping of Allometric Scaling. Functional Mapping of Drug Response with Allometric Scaling. Joint Functional Mapping of Drug Efficacy and Toxicity. Modeling Epistatic Interactions in Drug Response. Mapping Genotype-Environment Interactions in Drug Response. Nonparametric Functional Mapping of Drug Response
Semiparametric Functional Mapping of Drug Response. Author Index.