Stress Proteins in Medicine  book cover
1st Edition

Stress Proteins in Medicine

ISBN 9780824796235
Published October 18, 1995 by CRC Press
592 Pages

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Book Description

Provides a thorough overview of current knowledge of stress proteins in both normal and disease physiology and evaluates the potential for developing novel diagnostic, prophylactic, and therapeutic approaches to control human disease based on the latest stress-protein research.

Table of Contents


Stress Proteins as Molecular Chaperones
The Unique Role of Heat Shock Proteins in Infections
Clinical Implications of the Stress Response
T-Lymphocyte Recognition of Hsp 60 in Experimental Arthritis
Heat Shock Protein 60 and the Regulation of Autoimmunity

Stress Proteins and Specific Immune Responses

Immune Responses to Heat Shock Proteins in Reactive Arthritis
Juvenile Chronic Arthritis and Heat Shock Proteins
T-Cell Responses to Heat Shock Proteins in Rheumatoid Arthritis
Heat Shock Protein 60 Autoimmunity in Lyme Disease
Stress Proteins in Behçet's Disease and Experimental Uveitis
Stress Proteins in Systemic Lupus Erythematosus
Expression of and Immune Response to Heat Shock Protein 65 in Crohn's Disease
Stress Proteins in Multiple Sclerosis and Other Central Nervous System Diseases
Heat Shock Protein 60 and Insulin-Dependent Diabetes Mellitus
Protection Against Tumors by Stress Protein Gene Transfer
Immune Responses to Stress Proteins in Mycobacterial Infections
Heat Shock Proteins in Fungal Infections
Stress Proteins and Infertility
Heat Shock Proteins in Visceral Leishmaniasis
Role of Heat Shock Protein Immunity in Transplantation

Stress Proteins and Expression in Diseased Tissue

Lupus and Heat Shock Proteins
Stress Proteins in Inflammatory Liver Disease
Helicobacter pylori-Associated Chronic Gastritis
Jejunal Epithelial Cell Stress Protein Expression in Gluten-Induced Enteropathy (Celiac Disease)
Identification of Endogenous Heat Shock Protein 60 as an Autoantigen in Autoimmune NOD Mouse Diabetes
Expression of Stress Proteins in Diabetes Mellitus: Detection of a Heat Shock Protein 60-like Protein in Pancreatic RINm5F -Cell Plasma Membranes
Stress Proteins and Myocardial Protection
Heat Shock Proteins in Eosinophilic Inflammation
Heat Shock Proteins in Duchenne Muscular Dystrophy and Other Muscular Disease
Mitochondrial Neuromuscular Disease Associated with Partial Deficiency of Heat Shock Protein 60

Stress Proteins and Interactions with Proteins or Cells in Immunity

Heat Shock Proteins as Chaperones of Unique and Shared Antigenic Epitopes of Human Cancers: A Novel Approach to Vaccination
In Vivo Carrier Effect of Heat Shock Proteins in Conjugated Vaccine Constructs
Major Histocompatibility Complex Class Ib Molecules: A Role in the Presentation of Heat Shock Proteins to the Immune System?
Polyclonal Responses of T Cells to Heat Shock Proteins

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…a comprehensive overview.
…the editors have achieved a healthy balance between historical background, factual knowledge and informed conjecture.
"-Annals of the Rheumatic Diseases

"…an excellent resource.
"-Trends in Endocrinology and Metabolism

"…a valuable and necessary source of information for readers working in the various fields of medicine.