1st Edition

Structure of Antigens, Volume III



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ISBN 9780849392252
Published December 20, 1995 by CRC Press
432 Pages 18 B/W Illustrations

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Book Description

Volume 3 of Structure of Antigens presents analytical methods used to elucidate the structure of antigens. As in the first two volumes, this reference focuses on the structure and analysis of antibody binding sites. It brings together the structural basis of major types of antigens, including lysozyme, cytochrome c, muscle proteins, cereal and milk proteins, carbohydrate antigens, and more. Major groups of antigens associated with particular biological systems, such as the cytoskeleton, muscle proteins, and viral antigens, are discussed. This reference analyzes the molecular basis of antibody specificity and the structure of T cell epitopes.

Table of Contents

Thermodynamics of Antigen Binding and Evaluation of Humanized Antibodies, R.F. Kelley
Mutational Analysis of Antibody Binding Sites, L. Jin and J.A. Wells
Epitope Delineation Using Multiple Peptide Synthesis, S.J. Rodda, H.M. Geysen, and G. Tribbick
The Structure of T Cell Epitopes, S. Stevanovi´c and H.-G. Rammensee
Lysozyme: Antigenic Structure as Defined by Antibody and T Cell Responses, J.-C. Grivel and S.J. Smith-Gill
Cytochrome c Antigens, R. Jemmerson, J.M. Minnerath, C.M. Mueller, and S. Buron
Muscle Proteins, C. Larue
Microtubules as Antigens, A.M. Lambert, V. Stoppin, M. Vantard, J. Canady, and A.C. Schmit
Carbohydrate Antigens (Polysaccharides), D. Wang and E.A. Kabat
Antigenic Structure of Virus Envelope Glycoproteins, A.R. Neurath and A.K. Debnath
Antigenic Structure of Non-Enveloped Viruses, F. Brown
Cereal Seed Storage Proteins, J.H. Skerritt and A.S. Tatham
Milk Proteins, S. Kaminogawa and A. Ametani

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