Superantigens: Molecular Biology: Immunology, and Relevance to Human Disease, 1st Edition (Hardback) book cover

Superantigens

Molecular Biology: Immunology, and Relevance to Human Disease, 1st Edition

By Leung

CRC Press

624 pages

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Hardback: 9780824798130
pub: 1997-02-20
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Description

This up-to-date sourcebook covers viral and bacterial superantigens (SAgs) from molecular structure and immunological processes to pathology and treatment of superantigen-mediated human diseases. Discusses diseases beyond Toxic Shock Syndrome, such as autoimmune and inflammatory skin conditions, as well as the role of superantigens in other infectious diseases. Illustrated with molecular structures of superantigens.

Table of Contents

Historical Perspective of Superantigens and Their Biologic Activities, Donald Y. M. Leung, Brigitte T. Huber, and Patrick M. Schlievert

Immunobiology of MMTV Superantigens, Susan R. Ross

Structural Features of MMTV Superantigens, Gary Winslow, John W. Kappler, and Philippa Marrack

Interaction of Superantigens with MHC Class II Molecules, Pascal M. Lavoie, Rafick-Pierre Sékaly, Jacques Thibodeau,and François Denis

Superantigen in Rabies Virus and Its Involvement in Paralysis, Monique Lafon

Superantigen Associated with Epstein-Barr Virus: Potential Role in Tumor Formation, Natalie Sutkowski and Brigitte T. Huber

Toxic Shock Syndrome Toxin-1: Molecular Structure and Basis for T-Cell Recognition, Cathleen A. Earhart, David T. Mitchell, Debra L. Murray, Patrick M. Schlievert, and Douglas H. Ohlendorf

Comparison of Structures of Toxic Shock Syndrome Toxin-1 Unbound and Bound to a Class II Major Histocompatibility Molecule, David T. Mitchell, Patrick M. Schlievert, Douglas H. Ohlendorf, Jongsun Kim, Don C. Wiley, Robert G. Urban, and Jack L. Strominger

Staphylococcal Enterotoxin B and C: Structural Requirements for Superantigenic and Entertoxigenic Activities, Gregory A. Bohach

Staphylococcal Enterotoxin A, D and E: Structure and Function, Including Mechanism of T-Cell Superantigenicity, L. Anders Svensson, Elinor M. Schad, Michael Sundström, Per Antonsson, Terje Kalland, and Mikael Dohlsten

The Exfoliative Toxins of Staphylococcus aureus, John J. Iandolo and Stephen Keith Chapes

Molecular Genetics, Structure, and Immunobiology of Streptococcal Pyrogenic Exotoxins A and C, Michael H. Kim and Patrick M. Schlievert

Streptococcal Superantigen, Mitogenic Factor, and Pyrogenic Exotoxin B Expressed by Streptococcus pyogenes: Structure and Function, James M. Musser

Streptococcal M Protein: Role in Post-Streptococcal Autoimmunity, Malak Kotb

The Superantigen Mycoplasma arthritidis Mitogen (MAM): Physical Properties and Immunobiology, Kevin L. Knudtson, Allen D. Sawitzke, and Barry C. Cole

Characterization of a Superantigen Produced by Yersinia pseudotuberculosis, Jun Abe and Tae Takeda

B-Cell Superantigens and Their Biological Implications, Arnold I. Levinson and Lisa M. Kozlowski

Staphylococcal Toxic Shock Syndrome, Robert L. Deresiewicz

Streptococcal Toxic Shock Syndrome, Dennis L. Steves

Viral Superantigens in Humans: A Potential Role in HIV and CMV Infection, David N. Posnett

Superantigens in Autoimmunity: Their Role as Etiologic and Therapeutic Agents, Joel Schiffenbauer, Howard Johnson, and Jeanne Soos

Superantigens in Inflammatory Skin Diseases: A Role in Disease Maintenance and Induction, David A. Norris and Donald Y. M. Leung

Superantigens in Human Disease: Future Directions in Therapy and Elucidation of Disease. Pathogenesis, Donald Y. M. Leung and Patrick M. Schlievert

Subject Categories

BISAC Subject Codes/Headings:
MED044000
MEDICAL / Immunology
SCI049000
SCIENCE / Life Sciences / Biology / Molecular Biology