From the analytical to industrial preparative scale, this work provides a praxis-oriented overview of packed column supercritical fluid chromatography. It discusses and evaluates established applications and techniques, up-to-date and promising developments, and commercial instrumentation devices for use in industry. The book also reveals possibilities for problem solving and future innovations.
"There are many points of interest in the book that provide insight into using pSFC successfully. . .. . . .The use of fundamental principles and applications describes in this book provides an excellent justification for the complementary presence of SFC with GC and LC in all analytical laboratories. "
"This welcomed and definitive book. . .sets the record straight: SFC is here to stay and has an important part to play in modern chromatographic separation. "
". . .constitutes precious help for those involved in separation problems, a population fated to grow in the next years. "
Determination of solubility data with on-line packed column supercritical fluid chromatography; chemical basis for the instrumentation used in packed column supercritical fluid chromatography; analytical and preparative carbon dioxide chromatography with automated pressure control and different detectors; packed column supercritical fluid chromatography - evaporative light scattering detection; packed capillary column supercritical fluid chromatography using neat carbon dioxide; selectivity tuning in packed column supercritical fluid chromatography; subcritical fluid chromatography with organic modifiers on octadecyl packed columns - recent developments for the analysis of high molecular organic compounds; chiral chromatography using sub- and supercritical fluids; enantiomer separation by sub- and supercritical fluid chromatography on rationally designed chiral stationary phases; applications of packed column supercritical fluid chromatography in the development of drugs; packed column supercritical fluid chromatography in the development of polymer additives; fractionation of polymer homologs with packed column supercritical fluid chromatography; the use of supercritical fluids in environmental analysis; preparative supercritical fluid chromatography - grams, kilograms, and tons; production of high purity n-3 fatty acid-ethyl esters by process scale supercritical fluid chromatography.