Synthetic Peptide Vaccine Models : Design, Synthesis, Purification and Characterization book cover
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Synthetic Peptide Vaccine Models
Design, Synthesis, Purification and Characterization



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ISBN 9780367473280
March 1, 2021 Forthcoming by CRC Press
288 Pages 38 Color & 28 B/W Illustrations

 
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Book Description

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Table of Contents

Chapter 1. Background

Emine Ekici

Chapter 2. Introduction to Vaccination

Nezih Pişkinpaşa and Ömer Faruk Karasakal

Chapter 3. Fundamentals of Modern Peptide Synthesis

Korkut Ulucan and Muhsin Konuk

Chapter 4. Peptide Synthesis and Characterization Stages

Mustafa Kemal Gümüş

Chapter 5. Conjugation of Polymers with Biomolecules and Polymeric Vaccine Development Technologies

S. Arda Ozturkcan

Chapter 6. What are Polymeric Carriers?

Gülderen Karakuş and Dolunay Şakar Daşdan

Chapter 7. Conjugation and Other Methods in Polymeric Vaccines

Özgür Özay

Chapter 8. Polymeric Nanoparticle Preparation Methods

Mithat Çelebi

Chapter 9. Peptides in Brain Disorders

Hüseyin Ünübol and Gökben Hızlı Sayar

Chapter 10. Pseudo-proteins and related synthetic amino acid based polymers promising for constructing artificial vaccines

Ramaz Katsarava

Chapter 11. Peptide Vaccines in Cancer Diseases

Özge Öznur Özcan, Rümeysa Rabia Kocatürk, Fadime Canbolat

Chapter 12. Antioxidant Peptides

Rümeysa Rabia Kocatürk, Fatmanur Zehra Zelka, Özge Öznur Özcan, Fadime Canbolat

Chapter 13. Peptide Vaccine

Joel Lim Whye Ern, Tan Shen Leng, Tee Yi Na and Palaniarajan Vijayaraj Kumar

Chapter 14. Adjuvants Of Vaccine in Immunotoxicology

Fadime Canbolat

Chapter 15. Role of Epigenetics in Immunity and Immune Response to Vaccination

Ozan Tiryakioğlu

Chapter 16. "Omics" technologies in vaccine research

Sezer Okay

Chapter 17. Computer-Aided Epitope Identification and Design of Epitope Mimetics.

Greg Czyryca

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Author(s)

Biography

Assoc. Prof. Dr. Mesut Karahan graduated from Yildiz Technical University, Faculty of Arts and Sciences Department of Chemistry in 1999. Between 2001 and 2012, Dr. Karahan worked in Yildiz Technical University. He got his master’s degree in 2002 at the same university with his study titled "Ternary Polymer-Metal-Protein Complex Structure Models". Assoc. Prof. Dr. Karahan completed his Ph.D. studies in 2009 on "Development of Functional Biopolymer Systems Containing Metal”. He has been working at Üsküdar University since 2012. Working Areas: Vaccine Systems, Diagnostic Kit, Biochemistry, Biopolymer Systems, Peptide Synthesis, Proteins, Bioconjugation, Biopolymer-Metal-Peptide Complexes.